CPSS 2.0: a computational platform update for the analysis of small RNA sequencing data

被引：24

作者：

Wan, Changlin ^{[1
]}

Gao, Jianing ^{[1
]}

Zhang, Huan ^{[1
]}

Jiang, Xiaohua ^{[1
]}

Zang, Qiguang ^{[2
]}

Ban, Rongjun ^{[1
]}

Zhang, Yuanwei ^{[1
]}

Shi, Qinghua ^{[1
]}

机构：

[1] Univ Sci & Technol China, CAS Key Lab Innate Immun & Chron Dis, CAS Ctr Excellence Mol Cell Sci,Collaborat Innova, Sch Life Sci,Mol & Cell Genet Lab,Hefei Natl Lab, Hefei 230027, Anhui, Peoples R China

[2] Univ Sci & Technol China, Sch Informat Sci & Technol, Hefei 230027, Peoples R China

来源：

BIOINFORMATICS | 2017年 / 33卷 / 20期

基金：

中国国家自然科学基金; 以色列科学基金会;

关键词：

D O I：

10.1093/bioinformatics/btx066

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A Summary:Next-generation sequencing has been widely applied to understand the complexity of non-coding RNAs (ncRNAs) in the last decades. Here, we present CPSS 2.0, an updated version of CPSS 1.0 for small RNA sequencing data analysis, with the following improvements: (i) a substantial increase of supported species from 10 to 48; (ii) improved strategies applied to detect ncRNAs; (iii) more ncRNAs can be detected and profiled, such as lncRNA and circRNA; (iv) identification of differentially expressed ncRNAs among multiple samples; (v) enhanced visualization interface containing graphs and charts in detailed analysis results. The new version of CPSS is an efficient bioinformatics tool for users in non-coding RNA research.

引用

页码：3289 / 3291

页数：3

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