CPSS 2.0: a computational platform update for the analysis of small RNA sequencing data

被引：24
|
作者：
Wan, Changlin [1 ]
Gao, Jianing [1 ]
Zhang, Huan [1 ]
Jiang, Xiaohua [1 ]
Zang, Qiguang [2 ]
Ban, Rongjun [1 ]
Zhang, Yuanwei [1 ]
Shi, Qinghua [1 ]
机构：
[1] Univ Sci & Technol China, CAS Key Lab Innate Immun & Chron Dis, CAS Ctr Excellence Mol Cell Sci,Collaborat Innova, Sch Life Sci,Mol & Cell Genet Lab,Hefei Natl Lab, Hefei 230027, Anhui, Peoples R China
[2] Univ Sci & Technol China, Sch Informat Sci & Technol, Hefei 230027, Peoples R China
来源：
BIOINFORMATICS | 2017年 / 33卷 / 20期
基金：
中国国家自然科学基金; 以色列科学基金会;
关键词：
D O I：
10.1093/bioinformatics/btx066
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
A Summary:Next-generation sequencing has been widely applied to understand the complexity of non-coding RNAs (ncRNAs) in the last decades. Here, we present CPSS 2.0, an updated version of CPSS 1.0 for small RNA sequencing data analysis, with the following improvements: (i) a substantial increase of supported species from 10 to 48; (ii) improved strategies applied to detect ncRNAs; (iii) more ncRNAs can be detected and profiled, such as lncRNA and circRNA; (iv) identification of differentially expressed ncRNAs among multiple samples; (v) enhanced visualization interface containing graphs and charts in detailed analysis results. The new version of CPSS is an efficient bioinformatics tool for users in non-coding RNA research.
引用
收藏
页码：3289 / 3291
页数：3
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