Recruitment experience in a phase 0 trial of ABT-888, an inhibitor of poly (ADP-ribose) polymerase (PARP), in patients (pts) with advanced malignancies

被引:0
|
作者
Gutierrez, M.
Kummar, S.
Horneffer, Y.
Juwara, L.
Chen, A.
Melillo, G.
Pickeral, O.
Tomaszewski, J. E.
Murgo, A. J.
Doroshow, J. H.
机构
[1] NCI, Bethesda, MD 20892 USA
[2] SAIC Frederick Inc, Frederick, MD USA
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
14111
引用
收藏
页数:1
相关论文
共 50 条
  • [41] A phase I trial of veliparib, an inhibitor of poly(ADP-ribose) polymerase (PARP), and topotecan (TPT) in patients with solid tumors.
    Hendrickson, Andrea Elisabeth Wahner
    Menefee, Michael E.
    Hartmann, Lynn C.
    Long, Harry J.
    Northfelt, Donald W.
    Reid, Joel M.
    Boakye-Agyeman, Fleix
    Flatten, Karen S.
    Poirier, Guy G.
    Lensing, Janet
    Erlichman, Charles
    Kaufmann, Scott H.
    Haluska, Paul
    JOURNAL OF CLINICAL ONCOLOGY, 2015, 33 (15)
  • [42] Liquid chromatography-mass spectrometric assay for the quantitation in human plasma of ABT-888, an orally available, small molecule inhibitor of poly(ADP-ribose) polymerase
    Parise, Robert A.
    Shawaqfeh, Mohammad
    Egorin, Merrill J.
    Beumer, Jan H.
    JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2008, 872 (1-2): : 141 - 147
  • [43] Discovery of the Poly(ADP-ribose) Polymerase (PARP) Inhibitor 2-[(R)-2-methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide (ABT-888) for the Treatment of Cancer
    Penning, Thomas D.
    Zhu, Gui-Dong
    Gandhi, Viraj B.
    Gong, Jianchun
    Liu, Xuesong
    Shi, Yan
    Klinghofer, Vered
    Johnson, Eric F.
    Donawho, Cherrie K.
    Frost, David J.
    Bontcheva-Diaz, Velitchka
    Bouska, Jennifer J.
    Osterling, Donald J.
    Olson, Amanda M.
    Marsh, Kerman C.
    Luo, Yan
    Giranda, Vincent L.
    JOURNAL OF MEDICINAL CHEMISTRY, 2009, 52 (02) : 514 - 523
  • [44] Beneficial effect of poly(ADP-ribose) polymerase (PARP) inhibitor in acute photodamage
    Farkas, B
    Csete, B
    Magyarlaki, M
    Németh, J
    Tubak, V
    Nagy, PL
    Sümegi, B
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2002, 119 (03) : 740 - 740
  • [45] BMN-673 Poly [ADP-ribose] Polymerase (PARP) Inhibitor Oncolytic
    Gras, Jordi
    DRUGS OF THE FUTURE, 2013, 38 (12) : 813 - 819
  • [46] Pharmacodynamic and pathway analysis of three presumed inhibitors of poly (ADP-ribose) polymerase: ABT-888, AZD2281, and BSI201
    Ji, Jiuping
    Lee, Maxwell P.
    Kadota, Mitsutaka
    Zhang, Yiping
    Parchment, Ralph E.
    Tomaszewski, Joseph E.
    Doroshow, James H.
    CANCER RESEARCH, 2011, 71
  • [47] Myeloid malignancies in cancer patients treated with poly(ADP-ribose) polymerase (PARP) inhibitors: a case series
    Jennifer L. Oliveira
    Patricia T. Greipp
    Aruna Rangan
    Aminah Jatoi
    Phuong L. Nguyen
    Blood Cancer Journal, 12
  • [48] Myeloid malignancies in cancer patients treated with poly(ADP-ribose) polymerase (PARP) inhibitors: a case series
    Oliveira, Jennifer L.
    Greipp, Patricia T.
    Rangan, Aruna
    Jatoi, Aminah
    Nguyen, Phuong L.
    BLOOD CANCER JOURNAL, 2022, 12 (01)
  • [49] Integrated safety analysis of the poly (ADP-ribose) polymerase (PARP) inhibitor rucaparib in patients (pts) with ovarian cancer in the treatment and maintenance settings
    Kristeleit, R. S.
    Oza, A. M.
    Oaknin, A.
    Aghajanian, C.
    Tinker, A. V.
    Tredan, O.
    O'Malley, D. M.
    Leary, A.
    Konecny, G. E.
    Lorusso, D.
    Weberpals, J. I.
    Goble, S.
    Maloney, L.
    Cameron, T.
    Swisher, E.
    McNeish, I. A.
    Shapira-Frommer, R.
    Ledermann, J. A.
    Coleman, R. L.
    ANNALS OF ONCOLOGY, 2019, 30 : 409 - +