Recruitment experience in a phase 0 trial of ABT-888, an inhibitor of poly (ADP-ribose) polymerase (PARP), in patients (pts) with advanced malignancies

被引：0
|
作者：
Gutierrez, M.
Kummar, S.
Horneffer, Y.
Juwara, L.
Chen, A.
Melillo, G.
Pickeral, O.
Tomaszewski, J. E.
Murgo, A. J.
Doroshow, J. H.
机构：
[1] NCI, Bethesda, MD 20892 USA
[2] SAIC Frederick Inc, Frederick, MD USA
来源：
JOURNAL OF CLINICAL ONCOLOGY | 2007年 / 25卷 / 18期
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
14111
引用
收藏
页数：1
相关论文
共 50 条
  • [31] Correlation between inhibition of the activity of poly(ADP-ribose) polymerase (PARP) in human peripheral blood mononuclear cells (PBMCs) and tumor biopsies following treatment with ABT-888, an inhibitor of PARP
    Kummar, Shivaani
    Rubinstein, Larry
    Kinders, Robert
    Ji, Jiuping
    Parchment, Ralph
    Gutierrez, Martin
    Murgo, Anthony
    Chen, Alice
    Khin, Sonny
    Zhang, Yiping
    Simmons, Dwight
    Yancey, Mary Ann
    Allen, Deborah
    Horneffer, Yvonne
    Juwara, Lamin
    Chang, Richard
    Gordon, Gary
    Tomaszewski, Joseph
    Doroshow, James
    CANCER RESEARCH, 2009, 69
  • [32] Modulation of radiation response of non-small cell lung cancer cells with poly (ADP-ribose) polymerase inhibitor: ABT-888
    Hall, W. A.
    Wang, L.
    Clarke, J.
    Otterson, G.
    Wang, J. Z.
    Villalona, M.
    Hoang, T.
    Mayr, N.
    Ross, P.
    Grecula, J. C.
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2008, 72 (01): : S709 - S709
  • [33] Simultaneous determination of ABT-888, a poly (ADP-ribose) polymerase inhibitor, and its metabolite in human plasma by liquid chromatography/tandem mass spectrometry
    Wiegand, Richard
    Wu, Jianmei
    Sha, Xianyi
    LoRusso, Patricia
    Li, Jing
    JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2010, 878 (3-4): : 333 - 339
  • [34] A novel Poly(ADP-ribose) polymerase inhibitor, ABT-888, sensitizes malignant human cell lines to ionizing radiation under oxia and hypoxia
    Liu, S. K.
    Coackley, C.
    Bristow, R.
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2007, 69 (03): : S615 - S615
  • [35] Preclinical evaluation of Poly (ADP) Ribose Polymerase (PARP) enzyme inhibitor, ABT-888, in combination with cytotoxic agents in small cell lung cancer (SCLC)
    Owonikoko, Taofeek K.
    Zhang, Guojing
    Yue, Ping
    Ramalingam, Suresh
    Khuri, Fadlo
    Sun, Shi-Yong
    CANCER RESEARCH, 2011, 71
  • [36] The poly(ADP-Ribose) polymerase inhibitor ABT-888 reduces radiation-induced nuclear EGFR and augments head and neck tumor response to radiotherapy
    Nowsheen, Somaira
    Bonner, James A.
    Yang, Eddy S.
    RADIOTHERAPY AND ONCOLOGY, 2011, 99 (03) : 331 - 338
  • [37] A novel poly (ADP-ribose) polymerase inhibitor, ABT-888, sensitizes malignant human cell lines to ionizing radiation under both oxia and hypoxia
    Liu, S. K.
    Coackley, C.
    Bristow, R. G.
    RADIOTHERAPY AND ONCOLOGY, 2007, 84 : S40 - S40
  • [38] Role of ABT888, a Novel Poly(ADP-Ribose) Polymerase (PARP) Inhibitor in Countering Autophagy and Apoptotic Processes Associated to Spinal Cord Injury
    Casili, Giovanna
    Campolo, Michela
    Lanza, Marika
    Filippone, Alessia
    Scuderi, Sarah
    Messina, Salvatore
    Ardizzone, Alessio
    Esposito, Emanuela
    Paterniti, Irene
    MOLECULAR NEUROBIOLOGY, 2020, 57 (11) : 4394 - 4407
  • [39] Role of ABT888, a Novel Poly(ADP-Ribose) Polymerase (PARP) Inhibitor in Countering Autophagy and Apoptotic Processes Associated to Spinal Cord Injury
    Giovanna Casili
    Michela Campolo
    Marika Lanza
    Alessia Filippone
    Sarah Scuderi
    Salvatore Messina
    Alessio Ardizzone
    Emanuela Esposito
    Irene Paterniti
    Molecular Neurobiology, 2020, 57 : 4394 - 4407
  • [40] Poly (ADP-Ribose) Polymerase Inhibitor, ABT888, Improved Cisplatin Effect in Human Oral Cell Carcinoma
    Paterniti, Irene
    Scuderi, Sarah Adriana
    Casili, Giovanna
    Lanza, Marika
    Mare, Marzia
    Giuffrida, Raffella
    Colarossi, Cristina
    Portelli, Marco
    Cuzzocrea, Salvatore
    Esposito, Emanuela
    BIOMEDICINES, 2021, 9 (07)
12345