Schiff base complexes, cancer cell lines, and anticancer evaluation: a review

被引：8
|
作者：
Majid, Sheikh Abdul [1 ]
Mir, Jan Mohammad [1 ]
Jan, Gowhar [1 ]
Shalla, Aabid Hussain [1 ]
机构：
[1] IUST, Dept Chem, Awantipora Pulwama, India
来源：
JOURNAL OF COORDINATION CHEMISTRY | 2022年 / 75卷 / 15-16期
关键词：
Schiff base; cancer; cisplatin; MTT assay; metallodrugs; TRANSITION-METAL-COMPLEXES; X-RAY-STRUCTURE; CRYSTAL-STRUCTURE; ANTITUMOR-ACTIVITY; STRUCTURAL-CHARACTERIZATION; COBALT(III) COMPLEXES; BIOLOGICAL-ACTIVITY; GOLD COMPLEXES; DNA-BINDING; COPPER(II);
D O I：
10.1080/00958972.2022.2131402
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
This review examines the importance of Schiff base ligands and their metal complexes against cancer. The chemotherapeutic action of certain metal complexes especially cisplatin are currently used for treatment of cancer. The main limitation of such cancer related drugs is high toxicity and side effects. The development of new anticancer agents against several cell lines is described in this article. Based on reports from the last decade, we are still awaiting an efficient anticancer candidate.
引用
收藏
页码：2018 / 2038
页数：21
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