Schiff base complexes, cancer cell lines, and anticancer evaluation: a review

被引：8

作者：

Majid, Sheikh Abdul ^{[1
]}

Mir, Jan Mohammad ^{[1
]}

Jan, Gowhar ^{[1
]}

Shalla, Aabid Hussain ^{[1
]}

机构：

[1] IUST, Dept Chem, Awantipora Pulwama, India

来源：

JOURNAL OF COORDINATION CHEMISTRY | 2022年 / 75卷 / 15-16期

关键词：

Schiff base; cancer; cisplatin; MTT assay; metallodrugs; TRANSITION-METAL-COMPLEXES; X-RAY-STRUCTURE; CRYSTAL-STRUCTURE; ANTITUMOR-ACTIVITY; STRUCTURAL-CHARACTERIZATION; COBALT(III) COMPLEXES; BIOLOGICAL-ACTIVITY; GOLD COMPLEXES; DNA-BINDING; COPPER(II);

D O I：

10.1080/00958972.2022.2131402

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

This review examines the importance of Schiff base ligands and their metal complexes against cancer. The chemotherapeutic action of certain metal complexes especially cisplatin are currently used for treatment of cancer. The main limitation of such cancer related drugs is high toxicity and side effects. The development of new anticancer agents against several cell lines is described in this article. Based on reports from the last decade, we are still awaiting an efficient anticancer candidate.

引用

页码：2018 / 2038

页数：21

共 50 条

[21] Synthesis, characterization, anticancer and antibacterial evaluation of Schiff base ligands derived from hydrazone and their transition metal complexes
Fekri, Roghayeh
Salehi, Mehdi
Asadi, Asadollah
Kubicki, Maciej
INORGANICA CHIMICA ACTA, 2019, 484 : 245 - 254
[22] Synthesis and characterization of different complexes derived from Schiff base and evaluation as a potential anticancer, antimicrobial, and insecticide agent
Aroua, Lotfi M.
Alhag, Sadeq K.
Al-Shuraym, Laila A.
Messaoudi, Sabri
Mahyoub, Jazem A.
Alfaifi, Mohammad Y.
Al-Otaibi, Wafa Mohammed
SAUDI JOURNAL OF BIOLOGICAL SCIENCES, 2023, 30 (03)
[23] SYNTHESIS OF NEW NANO SCHIFF BASE COMPLEXES: X-RAY CRYSTALLOGRAPHY, THERMAL, ELECTROCHEMICAL AND ANTICANCER STUDIES OF NANO URANYL SCHIFF BASE COMPLEXES
Firuzabadi, Fahimeh Dehghani
Asadi, Zahra
Yousefi, Reza
BULLETIN OF THE CHEMICAL SOCIETY OF ETHIOPIA, 2018, 32 (01) : 89 - 100
[24] Manganese Schiff Base Complexes, Crystallographic Studies, Anticancer Activities, and Molecular Docking
Odularu, Ayodele Temidayo
JOURNAL OF CHEMISTRY, 2022, 2022
[25] Anticancer Effects of Heterocyclic Schiff Base Ligands and Their Metal Complexes on Leukemia Cells
Shekhany, B.
Ozer, F.
Aytar, E.
Bradosty, S. W.
Boyraz, M. U.
Gurol, A. O.
Shaikh, F. K.
Suzergoz, F.
INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 85 (04) : 953 - 961
[26] Synthesis, characterization, and anticancer activity of mononuclear Schiff-base metal complexes
Yin, Lili
Zhang, Shaonan
Zhou, Tao
Zhen'guang, Hu
Zhang, Shuhua
JOURNAL OF MOLECULAR STRUCTURE, 2023, 1275
[27] Preparation, characterization, antimicrobial and anticancer activities of Schiff base mixed ligand complexes
Abd El-Halim, H. F.
Omar, M. M.
Anwar, Mahmoud N.
JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY, 2017, 130 (02) : 1069 - 1083
[28] Preparation, characterization, antimicrobial and anticancer activities of Schiff base mixed ligand complexes
H. F. Abd El-Halim
M. M. Omar
Mahmoud N. Anwar
Journal of Thermal Analysis and Calorimetry, 2017, 130 : 1069 - 1083
[29] Schiff base metallodrugs in antimicrobial and anticancer chemotherapy applications: a comprehensive review
Shekhar, Shashank
Khan, Amarendra Mohan
Sharma, Shreya
Sharma, Bhasha
Sarkar, Anjana
EMERGENT MATERIALS, 2022, 5 (02) : 279 - 293
[30] Anticancer activities of various new metal complexes prepared from a Schiff base on A549 cell line
Aslan, Halime Guzin
Akkoc, Senem
Kokbudak, Zulbiye
INORGANIC CHEMISTRY COMMUNICATIONS, 2020, 111

← 1 2 3 4 5 →