Autoimmune thrombocytopenia in non-Hodgkin's lymphomas

被引：67

作者：

Hauswirth, Alexander W. ^{[1
]}

Skrabs, Cathrin ^{[1
]}

Schuetzinger, Christian ^{[1
]}

Raderer, Markus ^{[2
]}

Chott, Andreas ^{[3
]}

Valent, Peter ^{[1
]}

Lechner, Klaus ^{[1
]}

Jaeger, Ulrich ^{[1
]}

机构：

[1] Med Univ Vienna, Dept Med 1, Div Hematol & Hemostaseol, Wahringergurtel 18-20, A-1090 Vienna, Austria

[2] Med Univ Vienna, Oncol, Vienna, Austria

[3] Med Univ Vienna, Dept Pathol, Vienna, Austria

来源：

HAEMATOLOGICA | 2008年 / 93卷 / 03期

关键词：

autoimmune thrombocytopenias; non-Hodgkin's lymphoma;

D O I：

10.3324/haematol.11934

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Autoimmune thrombocytopenia is a common immune-hematologic complication in non-Hodgkin's lymphomas and may complicate the treatment. We analyzed an original series from our institute as well as published cases of non-Hodgkin's lymphomas (excluding chronic lymphocytic leukemia) associated with autoimmune thrombocytopenia with regard to demographic factors, prevalence in non-Hodgkin's lymphoma subtypes and treatment outcome. The male/female ratio is 1.75. Half of the cases occurred prior to diagnosis of lymphoma. Chemotherapy is the best treatment in many non-Hodgkin's lymphomas patients with autoimmune thrombocytopenia compared with standard treatment of autoimmune thrombocytopenia. Splenectomy is effective in splenic marginal zone lymphoma. Autoimmune thrombocytopenia in patients with non-Hodgkin's lymphomas is potentially life-threatening and difficult to treat.

引用

页码：447 / 450

页数：4

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