Non-Hodgkin's lymphomas and organic solvents

被引：23
|
作者：
Rêgo, MAV
Sousa, CSC
Kato, M
de Carvalho, AB
Loomis, D
Carvalho, FM
机构：
[1] Hlth Dept Bahia State, Workers Hlth Ctr, CESAT, BR-40110050 Salvador, BA, Brazil
[2] Univ Fed Bahia, Dept Prevent Med, Sch Med, BR-41170290 Salvador, BA, Brazil
[3] Univ N Carolina, Sch Publ Hlth, Dept Epidemiol, Chapel Hill, NC 27515 USA
来源：
JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE | 2002年 / 44卷 / 09期
关键词：
D O I：
10.1097/00043764-200209000-00010
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
Organic solvents have been suggested as a possible risk factor for non-Hodgkin's lymphomas (NHL). We studied 109 NHL incident cases and 276 controls with other cancers (199011996) in the city of Salvador, Brazil. Occupational exposure to organic solvents was evaluated through standardized questionnaires and defined by industrial hygienists, taking into account individuals' lifetime history. An association between occupational exposure to organic solvents and NHL was observed, OR = 1.67 (95 % CI, 0.97 to 2.87), especially among individuals less than 64 years, OR = 1.91 (95 % CI, 0.99 to 3.67), and among those who used domestic insecticides, OR = 2.24 (95 % CI, 1.01 to 3.97). Odds ratios were similar for nodal and diffuse NHL. These results suggest that organic solvents may contribute to the causation of NHL, especially among young individuals, and that synergism may play a role in the process of lymphomagenesis.
引用
收藏
页码：874 / 881
页数：8
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