Regulation of fetal male germ cell development by members of the TGFβ superfamily

被引：18
|
作者：
Spiller, Cassy [1 ]
Burnet, Guillaume [1 ]
Bowles, Josephine [1 ,2 ]
机构：
[1] Univ Queensland, Sch Biomed Sci, Brisbane, Qld 4072, Australia
[2] Univ Queensland, Inst Mol Biosci, Brisbane, Qld 4072, Australia
来源：
STEM CELL RESEARCH | 2017年 / 24卷
基金：
英国医学研究理事会;
关键词：
Germ cells; TGF beta; Activins; Nodal; Cripto; EMBRYONIC STEM-CELLS; RETINOIC ACID; ACTIVIN-A; SUPPRESSES MEIOSIS; TESTIS DEVELOPMENT; MOUSE TESTIS; MICE; CRIPTO; SEX; DIFFERENTIATION;
D O I：
10.1016/j.scr.2017.07.016
中图分类号：
Q813 [细胞工程];
学科分类号：
摘要：
There is now substantial evidence that members of the transforming growth factor-beta (TGF beta family) regulate germ cell development in the mouse fetal testis. Correct development of germ cells during fetal life is critical for establishment of effective spermatogenesis and for avoiding the formation of testicular germ cell cancer in later life. Here we consider the evidence for involvement of various TGF beta family members, attempt to reconcile discrepancies and clarify what we believe to be the likely in vivo roles of these factors. Crown Copyright (C) 2017 Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license.
引用
收藏
页码：174 / 180
页数：7
相关论文
共 50 条
  • [41] The TGFβ superfamily in stern cell biology and early mammalian embryonic development
    Beyer, Tobias A.
    Narimatsu, Masahiro
    Weiss, Alexander
    David, Laurent
    Wrana, Jeffrey L.
    BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2013, 1830 (02): : 2268 - 2279
  • [42] Insulin altered expression of members of the TGF-β superfamily in human retinal epithelial cell cultures
    Yeh, LCC
    Unda, R
    Vogt, R
    Tsin, AT
    Lee, JC
    FASEB JOURNAL, 2003, 17 (05): : A1020 - A1021
  • [43] Redox regulation of apoptosis by members of the TNF superfamily
    Shakibaei, M
    Schulze-Tanzil, G
    Takada, Y
    Aggarwal, BB
    ANTIOXIDANTS & REDOX SIGNALING, 2005, 7 (3-4) : 482 - 496
  • [44] Modeling human fetal germ cell development in vitro
    Childs, Andrew
    Saunders, Philippa
    Anderson, Richard
    BIOLOGY OF REPRODUCTION, 2008, : 300 - 300
  • [45] Fetal germ cell development in humans, a link with infertility
    Czukiewska, Sylwia M.
    Lopes, Susana M. Chuva de Sousa
    SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY, 2022, 131 : 58 - 65
  • [46] Age-dependent regulation of non-coding RNAs in male germ cell development
    Luk, Alfred C. S.
    Ng, Shuk Han
    Chan, Wai-Yee
    Lee, Tin-Lap
    FASEB JOURNAL, 2012, 26
  • [47] ULTRASTRUCTURE OF GERM CELL DEVELOPMENT IN HUMAN FETAL TESTIS
    GONDOS, B
    HOBEL, CJ
    ZEITSCHRIFT FUR ZELLFORSCHUNG UND MIKROSKOPISCHE ANATOMIE, 1971, 119 (01): : 1 - &
  • [48] Regulation of gonad formation and germ cell development
    Van Doren, Mark
    CELL STRUCTURE AND FUNCTION, 2004, 29 : 4 - 4
  • [49] Regulation of primordial germ cell development in the mouse
    De Felici, M
    INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY, 2000, 44 (06): : 575 - 580
  • [50] Regulation of the mitotic and meiotic cell cycles in the male germ line
    Wolgemuth, DJ
    Laurion, E
    Lele, KM
    RECENT PROGRESS IN HORMONE RESEARCH, VOL 57: REPRODUCTIVE HORMONES & HUMAN HEALTH, 2002, 57 : 75 - 101
12345