Three-component reaction of 2-alkynylbenzaldehyde, amine, and nucleophile using Lewis acid-surfactant combined catalyst in water

被引：74
|
作者：
Ye, Yang [1 ]
Ding, Qiuping [1 ,3 ]
Wu, He [1 ,2 ]
机构：
[1] Fudan Univ, Dept Chem, Shanghai 200433, Peoples R China
[2] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China
[3] Jiangxi Normal Univ, Analyt Ctr Phys & Chem, Nanchang 330027, Peoples R China
来源：
TETRAHEDRON | 2008年 / 64卷 / 07期
基金：
中国国家自然科学基金;
关键词：
Lewis acid-surfactant combined catalyst; water; ultrasonic; 1,2-dihydroisoquinoline;
D O I：
10.1016/j.tet.2007.11.055
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Lewis acid-surfactant combined catalyst (LASC) catalyzed three-component reactions of 2-alkynylbenzaldehyde, amines, and nucleophiles (alkyne, nitromethane, or diethyl phosphate) in water under ultrasonic conditions afforded the corresponding 1,2-dihydroisoquinoline derivatives in good yields. (c) 2007 Elsevier Ltd. All rights reserved.
引用
收藏
页码：1378 / 1382
页数：5
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