Caspase-8: Clipping off RIG-I Signaling

被引：3

作者：

Roth, Susanne ^{[1
]}

Ruland, Juergen ^{[1
,2
]}

机构：

[1] Tech Univ Munich, Klinikum Rechts Isar, Inst Mol Immunol, D-81675 Munich, Germany

[2] German Res Ctr Environm Hlth, Helmholtz Zentrum Munchen, Lab Signaling Immune Syst, D-85764 Neuherberg, Germany

来源：

IMMUNITY | 2011年 / 34卷 / 03期

关键词：

RECOGNITION; ACTIVATION; RECEPTORS; NEMO;

D O I：

10.1016/j.immuni.2011.03.011

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Activation of the RIG-I signaling molecule is essential for antiviral immunity but mechanisms downmodulating the response are ill defined. In this issue of Immunity, Rajput et al. (2011) describe caspase-8-mediated RIP1 cleavage as a key step for restricting RIG-I signaling.

引用

页码：283 / 285

页数：3

共 50 条

[41] Involvement of zebrafish RIG-I in NF-κB and IFN signaling pathways: Insights into functional conservation of RIG-I in antiviral innate immunity
Nie, Li
Zhang, Ying-sheng
Dong, Wei-ren
Xiang, Li-xin
Shao, Jian-zhong
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2015, 48 (01): : 95 - 101
[42] Multilayered regulations of RIG-I in the anti-viral signaling pathway
Kim, Nari
Now, Hesung
Nguyen, Nhung T. H.
Yoo, Joo-Yeon
JOURNAL OF MICROBIOLOGY, 2016, 54 (09) : 583 - 587
[43] Molecular interactions regulating RIG-I signaling to the innate antiviral response
Hiscott, John
Paz, Suzanne
Vilasco, Myriam
Arguello, Meztli
Lacoste, Judith
Zhao, Tiejun
Meurs, Eliane
Lin, Rongtuan
FASEB JOURNAL, 2008, 22
[44] RNA binding activates RIG-I by releasing an autorepressed signaling domain
Dickey, T. H.
Song, B.
Pyle, A. M.
SCIENCE ADVANCES, 2019, 5 (10)
[45] RIG-I like receptors and their signaling crosstalk in the regulation of antiviral immunity
Ramos, Hilario J.
Gale, Michael, Jr.
CURRENT OPINION IN VIROLOGY, 2011, 1 (03) : 167 - 176
[46] From Procaspase-8 to Caspase-8: Revisiting Structural Functions of Caspase-8
Zhao, Yang
Sui, Xin
Ren, Hong
JOURNAL OF CELLULAR PHYSIOLOGY, 2010, 225 (02) : 316 - 320
[47] RIG-I recognizes metabolite-capped RNAs as signaling ligands
Schweibenz, Brandon D.
Solotchi, Mihai
Hanpude, Pranita
Devarkar, Swapnil C.
Patel, Smita S.
NUCLEIC ACIDS RESEARCH, 2023, 51 (15) : 8102 - 8114
[48] Programming of RIG-I signaling through co-factor interactions
Dewey, Elyse C.
Tan, Min Jie Alvin
Hibberd, Martin
Gale, Michael J.
JOURNAL OF IMMUNOLOGY, 2016, 196
[49] A rapid RIG-I signaling relay mediates efficient antiviral response
Thoresen, Daniel T.
Galls, Drew
Gotte, Benjamin
Wang, Wenshuai
Pyle, Anna M.
MOLECULAR CELL, 2023, 83 (01) : 90 - +
[50] Multilayered regulations of RIG-I in the anti-viral signaling pathway
Nari Kim
Hesung Now
Nhung T. H. Nguyen
Joo-Yeon Yoo
Journal of Microbiology, 2016, 54 : 583 - 587

← 1 2 3 4 5 →