Cooccurring JAK2 V617F and R1063H mutations increase JAK2 signaling and neutrophilia in myeloproliferative neoplasms

被引:6
|
作者
Mambet, Cristina [1 ,2 ,3 ]
Babosova, Olga [4 ]
Defour, Jean-Philippe [2 ,5 ]
Leroy, Emilie [1 ,2 ]
Necula, Laura [3 ]
Stanca, Oana [6 ,7 ]
Tatic, Aurelia [7 ,8 ]
Berbec, Nicoleta [6 ,7 ]
Coriu, Daniel [7 ,8 ]
Belickova, Monika [9 ]
Kralova, Barbora [10 ]
Lanikova, Lucie [4 ]
Vesela, Jitka [9 ]
Pecquet, Christian [1 ,2 ]
Saussoy, Pascale [5 ]
Havelange, Violaine [11 ]
Diaconu, Carmen C. [3 ]
Divoky, Vladimir [10 ]
Constantinescu, Stefan N. [1 ,2 ,3 ]
机构
[1] Ludwig Inst Canc Res, Brussels Branch, Brussels, Belgium
[2] Catholic Univ Louvain, de Duve Inst, Brussels, Belgium
[3] Stefan S Nicolau Inst Virol, Mol Profiling Myeloproliferat Neoplasms & Acute L, Bucharest, Romania
[4] Acad Sci Czech Republ, Inst Mol Genet, Dept Cell & Dev Biol, Prague, Czech Republic
[5] Catholic Univ Louvain, Clin Univ St Luc, Dept Biol Clin, Brussels, Belgium
[6] Coltea Clin Hosp, Dept Hematol, Bucharest, Romania
[7] Carol Davila Univ Med & Pharm, Dept Radiol Oncol & Hematol, Bucharest, Romania
[8] Fundeni Clin Inst, Ctr Hematol & Bone Marrow Transplantat, Bucharest, Romania
[9] Inst Hematol & Blood Transfus, Prague, Czech Republic
[10] Palacky Univ, Fac Med & Dent, Dept Biol, Hnevotinska 3, CZ-77515 Olomouc, Czech Republic
[11] Clin Univ St Luc, Serv Hematol, Brussels, Belgium
关键词
ESSENTIAL THROMBOCYTHEMIA; POLYCYTHEMIA-VERA;
D O I
10.1182/blood-2018-04-843060
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页码:2695 / 2699
页数:7
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