Regulatory B cell phenotype and mechanism of action: the impact of stimulating conditions

被引：18
|
作者：
Wasik, Magdalena [1 ]
Nazimek, Katarzyna [1 ]
Bryniarski, Krzysztof [1 ]
机构：
[1] Jagiellonian Univ, Dept Immunol, Coll Med, 18 Czysta St, PL-31121 Krakow, Poland
来源：
MICROBIOLOGY AND IMMUNOLOGY | 2018年 / 62卷 / 08期
关键词：
autoimmune diseases; Breg cell; immunoregulation; infectious diseases; SYSTEMIC-LUPUS-ERYTHEMATOSUS; T-CELLS; B10; CELLS; STAPHYLOCOCCUS-AUREUS; IL-10; PRODUCTION; GRANZYME-B; AUTOIMMUNE INFLAMMATION; ADENOSINE PRODUCTION; IMMUNE SUPPRESSION; VIRUS INFECTION;
D O I：
10.1111/1348-0421.12636
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
A diverse population of regulatory B (Breg) cells reportedly exhibits significant immunomodulatory effects in various models of inflammatory responses and infectious diseases caused by bacteria, viruses or parasites. Breg cells contribute to maintenance of homeostasis via IL-10 production and multiple IL-10-independent mechanisms. The current review describes various phenotypic and functional subsets of Breg cells in autoimmune and infectious diseases and discusses the impacts of experimental conditions that have been found to drive Breg cell differentiation.
引用
收藏
页码：485 / 496
页数：12
相关论文
共 50 条
  • [1] Peripheral Regulatory B Cell Phenotype in Multiple Sclerosis Patients
    Habib, Jakob
    Deng, Jiusheng
    Pennati, Andrea
    Lava, Neil
    Galipeau, Jacques
    BLOOD, 2012, 120 (21)
  • [2] STIMULATING BANK COMPETITION THROUGH REGULATORY ACTION
    HORVITZ, PM
    JOURNAL OF FINANCE, 1965, 20 (01): : 1 - 13
  • [3] Mechanism of BLyS action in B cell immunity
    Do, RKG
    Chen-Kiang, S
    CYTOKINE & GROWTH FACTOR REVIEWS, 2002, 13 (01) : 19 - 25
  • [4] MECHANISM OF RESPIRATORY STIMULATING ACTION OF NORADRENALINE
    PAULET, G
    LEBARS, R
    LEGALL, M
    COMPTES RENDUS DES SEANCES DE LA SOCIETE DE BIOLOGIE ET DE SES FILIALES, 1972, 166 (10): : 1352 - 1354
  • [5] MECHANISM OF ACTION OF HUMAN B-CELL-ACTIVATING FACTOR .1. COMPARISON OF THE PLAQUE-STIMULATING ACTIVITY WITH THYMOCYTE-STIMULATING ACTIVITY
    WOOD, DD
    JOURNAL OF IMMUNOLOGY, 1979, 123 (05): : 2400 - 2407
  • [6] Characterization of Definitive Regulatory B Cell Subsets by Cell Surface Phenotype, Function and Context
    Neu, Savannah D.
    Dittel, Bonnie N.
    FRONTIERS IN IMMUNOLOGY, 2021, 12
  • [7] B cell targeting agents: mechanism of action in MS
    Cross, Anne H.
    MULTIPLE SCLEROSIS JOURNAL, 2018, 24 : 7 - 7
  • [8] Impact of cryopreservation on B cell chronic lymphocytic leukaemia phenotype
    Deneys, V
    Thiry, V
    Hougardy, N
    Mazzon, AM
    Leveugle, P
    De Bruyère, M
    JOURNAL OF IMMUNOLOGICAL METHODS, 1999, 228 (1-2) : 13 - 21
  • [9] A Novel Mechanism of Human Regulatory T cell Function in Proinflammatory Conditions
    Hester, Joanna
    Ospanova, Banu
    Touati, Nizar
    Wood, Kathryn J.
    TRANSPLANTATION, 2018, 102 : S331 - S331
  • [10] On the mechanism of the stimulating action of tension on the heart.
    Carlson, AJ
    AMERICAN JOURNAL OF PHYSIOLOGY, 1907, 18 (02): : 149 - 155
12345