Aldose reductase inhibitory activity studies of THERACURMIN

被引：1
|
作者：
Dahan, Zeyad A. [1 ]
Hussain, Sayyed [1 ]
Gyananath, G. [2 ]
Zubaidha, P. K. [3 ]
机构：
[1] Sir Sayyed Coll Arts Commerce & Sci, Aurangabad, Maharashtra, India
[2] SRTM Univ, Sch Life Sci, Nanded, India
[3] SRTM Univ, Sch Chem Sci, Nanded, India
来源：
NATURAL PRODUCT RESEARCH | 2018年 / 32卷 / 18期
关键词：
Aldose reductase; enzyme; bovine lens; THERACURMIN; DIABETIC COMPLICATIONS; CURCUMIN ANALOGS;
D O I：
10.1080/14786419.2017.1371165
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
THERACURMIN a commercially available nano-dispersion of curcumin used to treat after effects of alcohol has been evaluated for in vitro ARI activity on Aldose reductase isolated from the bovine lens. As envisaged, the product displays better ARI activity with IC50 value of 3M. The observed ARI activity of THERACURMIN is of therapeutic significance as the limited bioavailability of curcumin limits its clinical use. [GRAPHICS] .
引用
收藏
页码：2248 / 2251
页数：4
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