A new Neural Network ensemble heuristic for a predictor of the aldose reductase inhibitory activity

被引:0
|
作者
Parra-Hernandez, P [1 ]
Laxdal, EM [1 ]
Dimopoulos, NJ [1 ]
Alexiou, P [1 ]
机构
[1] Univ Victoria, Dept Elect & Comp Engn, Victoria, BC, Canada
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中图分类号
TP18 [人工智能理论];
学科分类号
081104 ; 0812 ; 0835 ; 1405 ;
摘要
In this paper, we present a mechanism to obtain a Neural Network-based model that predicts an enzyme inhibitory activity of a group of. compounds. The mechanism selects the compounds, among a sparse set of that should be used to obtain models of the inhibitory activity of interest. That is, the mechanism is aimed to the selection of a training set of compounds which will ensure that the training of a Neural Network-based model will result in a system capable of generalization.
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页码:838 / 843
页数:6
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