NUCLEI SEGMENTATION OF FLUORESCENCE MICROSCOPY IMAGES BASED ON MIDPOINT ANALYSIS AND MARKED POINT PROCESS

被引:0
|
作者
Gadgil, Neeraj J. [1 ]
Salama, Paul [2 ]
Dunn, Kenneth W. [3 ]
Delp, Edward J. [1 ]
机构
[1] Purdue Univ, Sch Elect & Comp Engn, Video & Image Proc Lab, W Lafayette, IN 47907 USA
[2] Indiana Univ Purdue Univ, Dept Elect & Comp Engn, Indianapolis, IN 46202 USA
[3] Indiana Univ, Sch Med, Div Nephrol, Indianapolis, IN USA
关键词
biomedical image segmentation; marked point process; fluorescence microscopy; 2-PHOTON MICROSCOPY; EXTRACTION; ALGORITHM; DYNAMICS; KIDNEY; SPACES; MODEL;
D O I
暂无
中图分类号
TP18 [人工智能理论];
学科分类号
081104 ; 0812 ; 0835 ; 1405 ;
摘要
Microscope image analysis is challenging because of non-uniform brightness, decreasing image contrast with tissue depth, poor edge details and irregular and unknown structures. In this paper, we present a nuclei segmentation and counting method using midpoint analysis, shape-based function optimization and a MPP simulation with a spatial birth-death process. Preliminary results demonstrate efficacy of the proposed method.
引用
收藏
页码:37 / 40
页数:4
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