EFFICIENT SYNTHESIS OF UREA DERIVATIVES VIA A SEQUENTIAL ONE-POT NUCLEOPHILIC ADDITION/UGI FIVE-COMPONENT REACTION UNDER SOLVENT-FREE CONDITIONS

被引：3

作者：

Azizian, Javad ^{[1
]}

Yadollahzadeh, Khadijeh ^{[2
]}

Tahermansouri, Hasan ^{[3
]}

Khoei, Davood Chobfrosh ^{[4
]}

Delbari, Akram Sadat ^{[5
]}

机构：

[1] Islamic Azad Univ, Dept Chem, Sci & Res Branch, Tehran, Iran

[2] Islamic Azad Univ, Dept Chem, Aliabad Katoul Branch, Aliabad Katoul, Iran

[3] Islamic Azad Univ, Ayatollah Amoli Branch, Dept Chem, Amol, Iran

[4] Islamic Azad Univ, Shabestar Branch, Dept Chem, Shabestar, Iran

[5] Islamic Azad Univ, Islamshahr Branch, Dept Chem, Islamshahr, Iran

来源：

SYNTHETIC COMMUNICATIONS | 2012年 / 42卷 / 14期

关键词：

Five-component reaction; nucleophilic addition; one-pot; solvent-free; Ugi reaction; urea derivatives; MULTICOMPONENT REACTIONS; UGI REACTION; ACID; CONDENSATION; SCAFFOLDS; DISCOVERY;

D O I：

10.1080/00397911.2011.553697

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Urea polyfunctional derivatives were successfully synthesized via a one-pot, five-component nucleophilic addition/Ugi reaction sequence. Simplicity, solvent-free conditions, and good yields of products are advantages of this method.

引用

页码：2110 / 2120

页数：11

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