An Efficient and Facile Synthesis of Pyrimidine and Quinazoline Derivatives via One-Pot Three-Component Reaction under Solvent-Free Conditions

被引：11
|
作者：
Rong, Liangce [1 ]
Han, Hongxia [1 ]
Wang, Haiying [1 ]
Jiang, Hong [1 ]
Tu, Shuajiang [1 ]
Shi, Daqing [1 ]
机构：
[1] Xuzhou Normal Univ, Dept Chem, Key Lab Biotechnol Med Plant, Xuzhou 221116, Jiangsu, Peoples R China
来源：
JOURNAL OF HETEROCYCLIC CHEMISTRY | 2009年 / 46卷 / 02期
关键词：
HETEROCYCLES; INHIBITORS; CONDENSATIONS; ABSENCE;
D O I：
10.1002/jhet.43
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient and convenient method for the preparation of pyrimidine and quinazoline derivatives by the one-pot reaction of aromatic aldehydes, cyclic ketones and guanidine carbonate, in the presence of sodium hydroxide under solvent-free condition was reported. This method has the advantages of excellent yields, mild reaction conditions, easy work-up, and being environmentally friendly over the existing procedures.
引用
收藏
页码：152 / 157
页数：6
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