The A, C, G, and T of Genome Assembly

被引：7
|
作者：
Wajid, Bilal [1 ]
Sohail, Muhammad U. [2 ]
Ekti, Ali R. [3 ]
Serpedin, Erchin [4 ]
机构：
[1] Univ Engn & Technol, Dept EE, Lahore 54890, Punjab, Pakistan
[2] Govt Coll Univ, Dept Physiol, Faisalabad 38000, Punjab, Pakistan
[3] Gannon Univ, Dept ECE, Erie, PA 16501 USA
[4] Texas A&M Univ, Dept ECE, College Stn, TX 77840 USA
来源：
BIOMED RESEARCH INTERNATIONAL | 2016年 / 2016卷
关键词：
SHORT DNA-SEQUENCES; ERROR-CORRECTION; QUALITY-CONTROL; ALGORITHM; ACCURACY; MILLIONS; IMPROVE; ADAPTER; VELVET; VIEWER;
D O I：
10.1155/2016/6329217
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Genome assembly in its two decades of history has produced significant research, in terms of both biotechnology and computational biology. This contribution delineates sequencing platforms and their characteristics, examines key steps involved in filtering and processing raw data, explains assembly frameworks, and discusses quality statistics for the assessment of the assembled sequence. Furthermore, the paper explores recent Ubuntu-based software environments oriented towards genome assembly as well as some avenues for future research.
引用
收藏
页数：10
相关论文
共 50 条
  • [11] Genome assembly and haplotyping with Hi-C
    Korbel, Jan O.
    Lee, Charles
    NATURE BIOTECHNOLOGY, 2013, 31 (12) : 1099 - 1101
  • [12] Genome assembly and haplotyping with Hi-C
    Jan O Korbel
    Charles Lee
    Nature Biotechnology, 2013, 31 : 1099 - 1101
  • [13] C-C-A-G-G-C-M5C-T-G-G - HELICAL FINE-STRUCTURE, HYDRATION, AND COMPARISON WITH C-C-A-G-G-C-C-T-G-G
    HEINEMANN, U
    HAHN, M
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1992, 267 (11) : 7332 - 7341
  • [14] BINDING OF AN ANTITUMOR DRUG TO DNA NETROPSIN AND C-G-C-G-A-A-T-T-BRC-G-C-G
    KOPKA, ML
    YOON, C
    GOODSELL, D
    PJURA, P
    DICKERSON, RE
    JOURNAL OF MOLECULAR BIOLOGY, 1985, 183 (04) : 553 - 563
  • [15] Absence of minor groove monovalent cations in the crosslinked dodecamer C-G-C-G-A-A-T-T-C-G-C-G
    Chiu, TK
    Kaczor-Grzeskowiak, M
    Dickerson, RE
    JOURNAL OF MOLECULAR BIOLOGY, 1999, 292 (03) : 589 - 608
  • [16] The genome-wide landscape of C:G > T:A polymorphism at the CpG contexts in the human population
    Jeonghwan Youk
    Yohan An
    Seongyeol Park
    June-Koo Lee
    Young Seok Ju
    BMC Genomics, 21
  • [17] The genome-wide landscape of C:G > T:A polymorphism at the CpG contexts in the human population
    Youk, Jeonghwan
    An, Yohan
    Park, Seongyeol
    Lee, June-Koo
    Ju, Young Seok
    BMC GENOMICS, 2020, 21 (01)
  • [18] AN EFFICIENT CHEMICAL SYNTHESIS OF A BIOLOGICALLY FUNCTIONAL DNA MOLECULE, 5'D(A-T-G-G-G-T-T-T-C-T-T-C-G-C-)3', THROUGH THE PHOSPHOTRIESTER APPROACH
    BALGOBIN, N
    CHATTOPADHYAYA, J
    CHEMICA SCRIPTA, 1982, 20 (03): : 133 - 138
  • [19] THE PRIMARY-MODE OF BINDING OF CISPLATIN TO A B-DNA DODECAMER - C-G-C-G-A-A-T-T-C-G-C-G
    WING, RM
    PJURA, P
    DREW, HR
    DICKERSON, RE
    EMBO JOURNAL, 1984, 3 (05): : 1201 - 1206
  • [20] CRYSTAL-STRUCTURE OF C-T-C-T-C-G-A-G-A-G - IMPLICATIONS FOR THE STRUCTURE OF THE HOLLIDAY JUNCTION
    GOODSELL, DS
    GRZESKOWIAK, K
    DICKERSON, RE
    BIOCHEMISTRY, 1995, 34 (03) : 1022 - 1029
12345