2,5-Disubstituted furans from 1,4-alkynediols

被引：44
|
作者：
Pridmore, Simon J. [1 ]
Slatford, Paul A. [1 ]
Williams, Jonathan M. J. [1 ]
机构：
[1] Univ Bath, Dept Chem, Bath BA2 7AY, Avon, England
来源：
TETRAHEDRON LETTERS | 2007年 / 48卷 / 29期
基金：
英国工程与自然科学研究理事会;
关键词：
D O I：
10.1016/j.tetlet.2007.05.069
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
1-4-Alkynediols serve as readily available starting materials for isomerisation to 1,4-diketones, which can be converted in situ into the corresponding furans by acid-catalysed dehydration. A range of 2,5-disubstituted furans was prepared using the ruthenium-based catalyst Ru(PPh3)(3)(CO)H-2 with Xantphos at 1 mol % loading. (C) 2007 Published by Elsevier Ltd.
引用
收藏
页码：5111 / 5114
页数：4
相关论文
共 50 条
  • [41] Proximity-Induced Ligation and One-Pot Macrocyclization of 1,4-Diketone-Tagged Peptides Derived from 2,5-Disubstituted Furans upon Release from the Solid Support
    Manicardi, Alex
    Theppawong, Atiruj
    Van Troys, Marleen
    Madder, Annemieke
    ORGANIC LETTERS, 2023, 25 (36) : 6618 - 6622
  • [42] Synthesis and antimicrobial activity of some 1,4-disubstituted thiosemicarbazide and 2,5-disubstituted 1,3,4-thiadiazole derivatives
    Rollas, S
    Karakus, S
    Durgun, BB
    Kiraz, M
    Erdeniz, H
    FARMACO, 1996, 51 (12): : 811 - 814
  • [43] Diastereoselective synthesis of 2,5-disubstituted tetrahydrofurans
    Jalce, Gael
    Franck, Xavier
    Figadere, Bruno
    TETRAHEDRON-ASYMMETRY, 2009, 20 (22) : 2537 - 2581
  • [44] SYNTHETIC ROUTES TO 2,5-DISUBSTITUTED TETRAHYDROFURANS
    HARMANGE, JC
    FIGADERE, B
    TETRAHEDRON-ASYMMETRY, 1993, 4 (08) : 1711 - 1754
  • [45] THE STEREOCHEMISTRY OF SEVERAL 2,5-DISUBSTITUTED DIOXANES
    SUMMERBELL, RK
    STEPHENS, JR
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1954, 76 (24) : 6401 - 6407
  • [46] STEREOSELECTIVITY IN THE SYNTHESIS OF 2,5-DISUBSTITUTED PYRROLIDINES
    KINSMAN, R
    LATHBURY, D
    VERNON, P
    GALLAGHER, T
    JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1987, (04) : 243 - 244
  • [47] A NEW SYNTHESIS OF 2,5-DISUBSTITUTED PYRIDINES
    GIAM, CS
    STOUT, JL
    JOURNAL OF THE CHEMICAL SOCIETY D-CHEMICAL COMMUNICATIONS, 1970, (08): : 478 - &
  • [48] NEW SYNTHESIS OF 2,5-DISUBSTITUTED THIOPHENES
    SMUTNY, EJ
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1969, 91 (01) : 208 - &
  • [49] SOME DERIVATIVES OF 2,5-DISUBSTITUTED PYRIDINE
    DELARGE, J
    FARMACO-EDIZIONE SCIENTIFICA, 1974, 29 (02): : 101 - 108
  • [50] POLYESTERS OF 2,5-DISUBSTITUTED FURAN AND TETRAHYDROFURAN
    MOORE, JA
    KELLY, JE
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1974, : 85 - 85
12345