2,5-Disubstituted furans from 1,4-alkynediols

被引：44
|
作者：
Pridmore, Simon J. [1 ]
Slatford, Paul A. [1 ]
Williams, Jonathan M. J. [1 ]
机构：
[1] Univ Bath, Dept Chem, Bath BA2 7AY, Avon, England
来源：
TETRAHEDRON LETTERS | 2007年 / 48卷 / 29期
基金：
英国工程与自然科学研究理事会;
关键词：
D O I：
10.1016/j.tetlet.2007.05.069
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
1-4-Alkynediols serve as readily available starting materials for isomerisation to 1,4-diketones, which can be converted in situ into the corresponding furans by acid-catalysed dehydration. A range of 2,5-disubstituted furans was prepared using the ruthenium-based catalyst Ru(PPh3)(3)(CO)H-2 with Xantphos at 1 mol % loading. (C) 2007 Published by Elsevier Ltd.
引用
收藏
页码：5111 / 5114
页数：4
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