Multiple Placental Infarcts in a Pregnant Woman with Essential Thrombocythemia

被引：3

作者：

Edahiro, Yoko ^{[1
]}

Ando, Jun ^{[1
]}

Suzuki, Toshifumi ^{[2
]}

Fukumura, Yuki ^{[3
]}

Masuda, Azuchi ^{[1
]}

Sakayori, Shiori ^{[2
]}

Takeda, Jun ^{[2
]}

Maruyama, Yojiro ^{[2
]}

Makino, Shintaro ^{[1
]}

Itakura, Atsuo ^{[2
]}

Komatsu, Norio ^{[1
]}

机构：

[1] Juntendo Univ, Sch Med, Dept Hematol, Tokyo, Japan

[2] Juntendo Univ, Sch Med, Dept Obstet & Gynecol, Tokyo, Japan

[3] Juntendo Univ, Sch Med, Dept Human Pathol, Tokyo, Japan

来源：

INTERNAL MEDICINE | 2018年 / 57卷 / 24期

基金：

日本学术振兴会;

关键词：

myeloproliferative neoplasms; essential thrombocythemia; pregnancy; placental infarcts; aspirin; low-molecular-weight heparin; MYELOPROLIFERATIVE NEOPLASMS; COMPLICATIONS; MANAGEMENT; JAK2; RISK;

D O I：

10.2169/internalmedicine.1311-18

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Myeloproliferative neoplasms (MPNs), including polycythemia vera, essential thrombocythemia (ET), and primary myelofibrosis, mainly occur in older patients, but have also been reported in younger patients. A "second peak'' occurs in female patients in their thirties, particularly in ET; thus, the management of pregnancy is often discussed. We herein present the case of a 33-year-old woman with a high platelet count and multiple placental infarcts during delivery who was subsequently diagnosed with ET. Although there are no worldwide guidelines for the management of MPNs in pregnancy, the risk of thrombosis is markedly increased in these patients, and antithrombotic therapy should be considered.

引用

页码：3647 / 3650

页数：4

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