Myeloproliferative neoplasms (MPNs), including polycythemia vera, essential thrombocythemia (ET), and primary myelofibrosis, mainly occur in older patients, but have also been reported in younger patients. A "second peak'' occurs in female patients in their thirties, particularly in ET; thus, the management of pregnancy is often discussed. We herein present the case of a 33-year-old woman with a high platelet count and multiple placental infarcts during delivery who was subsequently diagnosed with ET. Although there are no worldwide guidelines for the management of MPNs in pregnancy, the risk of thrombosis is markedly increased in these patients, and antithrombotic therapy should be considered.
机构:
Mayo Clin, Dept Med, Div Hematol, 200 First St SW, Rochester, MN 55905 USAMayo Clin, Dept Med, Div Hematol, 200 First St SW, Rochester, MN 55905 USA
Tefferi, Ayalew
Pardanani, Animesh
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机构:
Mayo Clin, Dept Med, Div Hematol, 200 First St SW, Rochester, MN 55905 USAMayo Clin, Dept Med, Div Hematol, 200 First St SW, Rochester, MN 55905 USA
Pardanani, Animesh
NEW ENGLAND JOURNAL OF MEDICINE,
2019,
381
(22):
: 2135
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2144