Antifungal Resistance Trends of Candida auris Clinical Isolates in New York and New Jersey from 2016 to 2020

被引：34

作者：

Kilburn, Shannon ^{[1
]}

Innes, Gabriel ^{[2
]}

Quinn, Monica ^{[1
]}

Southwick, Karen ^{[3
]}

Ostrowsky, Belinda ^{[4
]}

Greenko, Jane A. ^{[5
]}

Lutterloh, Emily ^{[1
,6
]}

Greeley, Rebecca ^{[2
]}

Magleby, Reed ^{[2
]}

Chaturvedi, Vishnu ^{[1
]}

Chaturvedi, Sudha ^{[1
,6
]}

机构：

[1] New York State Dept Hlth, Albany, NY 12202 USA

[2] New Jersey Dept Hlth, Trenton, NJ USA

[3] New York State Dept Hlth, New Rochelle, NY USA

[4] CDC, Ctr Dis Control & Prevent, Atlanta, GA 30333 USA

[5] New York State Dept Hlth, Cent Islip, NY USA

[6] State Univ Albany Sch Publ Hlth, Albany, NY 12222 USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2022年 / 66卷 / 03期

关键词：

antifungals; Candida auris; minimum inhibitory concentration; epidemiological cutoff;

D O I：

10.1128/aac.02242-21

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

About 55% of U.S. Candida auris clinical cases were reported from New York and New Jersey from 2016 through 2020. Nearly all New York-New Jersey clinical isolates (99.8%) were fluconazole resistant, and 50% were amphotericin B resistant. Echinocandin resistance increased from 0% to 4% and pan-resistance increased from 0 to C. auris clinical isolates but not for New Jersey, highlighting the regional differences. About 55% of U.S. Candida auris clinical cases were reported from New York and New Jersey from 2016 through 2020. Nearly all New York-New Jersey clinical isolates (99.8%) were fluconazole resistant, and 50% were amphotericin B resistant. Echinocandin resistance increased from 0% to 4% and pan-resistance increased from 0 to C. auris clinical isolates but not for New Jersey, highlighting the regional differences.

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页数：5

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