Antifungal Resistance Trends of Candida auris Clinical Isolates in New York and New Jersey from 2016 to 2020

被引:34
|
作者
Kilburn, Shannon [1 ]
Innes, Gabriel [2 ]
Quinn, Monica [1 ]
Southwick, Karen [3 ]
Ostrowsky, Belinda [4 ]
Greenko, Jane A. [5 ]
Lutterloh, Emily [1 ,6 ]
Greeley, Rebecca [2 ]
Magleby, Reed [2 ]
Chaturvedi, Vishnu [1 ]
Chaturvedi, Sudha [1 ,6 ]
机构
[1] New York State Dept Hlth, Albany, NY 12202 USA
[2] New Jersey Dept Hlth, Trenton, NJ USA
[3] New York State Dept Hlth, New Rochelle, NY USA
[4] CDC, Ctr Dis Control & Prevent, Atlanta, GA 30333 USA
[5] New York State Dept Hlth, Cent Islip, NY USA
[6] State Univ Albany Sch Publ Hlth, Albany, NY 12222 USA
关键词
antifungals; Candida auris; minimum inhibitory concentration; epidemiological cutoff;
D O I
10.1128/aac.02242-21
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
About 55% of U.S. Candida auris clinical cases were reported from New York and New Jersey from 2016 through 2020. Nearly all New York-New Jersey clinical isolates (99.8%) were fluconazole resistant, and 50% were amphotericin B resistant. Echinocandin resistance increased from 0% to 4% and pan-resistance increased from 0 to C. auris clinical isolates but not for New Jersey, highlighting the regional differences. About 55% of U.S. Candida auris clinical cases were reported from New York and New Jersey from 2016 through 2020. Nearly all New York-New Jersey clinical isolates (99.8%) were fluconazole resistant, and 50% were amphotericin B resistant. Echinocandin resistance increased from 0% to 4% and pan-resistance increased from 0 to C. auris clinical isolates but not for New Jersey, highlighting the regional differences.
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页数:5
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