Roles of Microtubule Bias and Joining in the Self-Organization of Microtubule Driven by Dynein C - A Modeling Study

被引:0
|
作者
Chen, Q. [1 ]
Li, D. Y. [1 ,2 ]
Oiwa, K. [3 ]
机构
[1] Univ Alberta, Dept Biomed Engn, Edmonton, AB T6G 2V2, Canada
[2] Univ Alberta, Dept Chem & Mat Engn, Edmonton, AB T6G 2V4, Canada
[3] NICT Biocommun, Kansai Adv Res Ctr, Kobe, Hyogo 6512492, Japan
关键词
Self-organization; Microtubule; Dynein C; MT bias; MT joining; MOTOR PROTEIN; KINESIN; TRACKS;
D O I
暂无
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Microtubules driven by dynein protein motors may form self-organized circular patterns, understanding which could be of importance to the development of potential nano-bio-machines. It was expected that the microtubule bias and joining could play crucial roles in self-organized movement of microtubules. A Monte Carlo modeling study was conducted to confirm and evaluate contributions of these two parameters to self-organization of microtubules.
引用
收藏
页码:1497 / +
页数:3
相关论文
共 50 条
  • [31] The C1 microtubule of the central apparatus plays a role in defining regions of dynein-driven microtubule sliding
    Wargo, MJ
    Smith, EF
    MOLECULAR BIOLOGY OF THE CELL, 2002, 13 : 192A - 192A
  • [32] Active Self-Organization of Actin-Microtubule Composite Self-Propelled Rods
    Farhadi, Leila
    Do Rosario, Carline Fermino
    Debold, Edward P.
    Baskaran, Aparna
    Ross, Jennifer L.
    FRONTIERS IN PHYSICS, 2018, 6
  • [33] Self-organization of a radial microtubule array in cytoplasmic fragments of melanophores involves the formation of a new microtubule organizing center.
    Vorobjev, IA
    Malikov, VP
    Rodionov, VI
    MOLECULAR BIOLOGY OF THE CELL, 2000, 11 : 360A - 360A
  • [34] Self-organization of an acentrosomal microtubule network at the basal cortex of polarized epithelial cells
    Reilein, A
    Yamada, S
    Nelson, WJ
    JOURNAL OF CELL BIOLOGY, 2005, 171 (05): : 845 - 855
  • [35] Effects of different PRC1 constructs on microtubule assembly and self-organization
    Bourdeau, Julia F.
    Martin, Ariana
    Davis, Imara
    Chauhan, Prashali
    Ross, Jennifer L.
    BIOPHYSICAL JOURNAL, 2024, 123 (03) : 273A - 273A
  • [36] Effects of spatial dimensionality and steric interactions on microtubule-motor self-organization
    Rickman, Jamie
    Nedelec, Francois
    Surrey, Thomas
    PHYSICAL BIOLOGY, 2019, 16 (04)
  • [37] Dynamic self-organization and polymorphism of microtubule assembly through active interactions with kinesin
    Tamura, Yoshiki
    Kawamura, Ryuzo
    Shikinaka, Kazuhiro
    Kakugo, Akira
    Osada, Yoshihito
    Gong, Jian Ping
    Mayama, Hiroyuki
    SOFT MATTER, 2011, 7 (12) : 5654 - 5659
  • [38] Self-organization of plant microtubule arrays can be modeled with l-system fractals
    Wawrowsky, K
    Mole-Bajer, J
    Wolf, R
    Bajer, A
    MOLECULAR BIOLOGY OF THE CELL, 1999, 10 : 265A - 265A
  • [39] CLASP Modulates Microtubule-Cortex Interaction during Self-Organization of Acentrosomal Microtubules
    Ambrose, J. Christian
    Wasteneys, Geoffrey O.
    MOLECULAR BIOLOGY OF THE CELL, 2008, 19 (11) : 4730 - 4737
  • [40] Augmin-dependent microtubule self-organization drives kinetochore fiber maturation in mammals
    Almeida, Ana C.
    Soares-de-Oliveira, Joana
    Drpic, Danica
    Cheeseman, Liam P.
    Damas, Joana
    Lewin, Harris A.
    Larkin, Denis M.
    Aguiar, Paulo
    Pereira, Antonio J.
    Maiato, Helder
    CELL REPORTS, 2022, 39 (01):