Two-stage enzyme mediated drug release from LMWG hydrogels

被引:119
|
作者
van Bommel, KJC
Stuart, MCA
Feringa, BL
van Esch, J
机构
[1] Biomade Technol Fdn, NL-9747 AG Groningen, Netherlands
[2] Univ Groningen, Stratingh Inst, Dept Organ & Mol Inorgan Chem, NL-9747 AG Groningen, Netherlands
关键词
D O I
10.1039/b507157g
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
An enzymatically cleavable low molecular weight gelator-(model) drug conjugate system can be employed to effect a two-step enzyme mediated drug release, demonstrating the potential of LMWG systems for the development of drug delivery devices.
引用
收藏
页码:2917 / 2920
页数:4
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