+276G>T Single Nucleotide Polymorphism in the Adiponectine (APM1) Gene in Donors from the Kharkiv Population

被引：0
|
作者：
Atramentova, L. A. [1 ]
Poltorak, V. V. [1 ]
Tyzhnenko, T. V. [1 ]
Gorshunskaya, M. Yu. [2 ]
Pochernyaev, A. R. [1 ]
机构：
[1] Ukrainian Acad Sci, Danilevskii Inst Problems Endocrine Pathol, Kharkov, Ukraine
[2] Kharkiv Med Acad Postgrad Educ, Kharkov, Ukraine
来源：
CYTOLOGY AND GENETICS | 2010年 / 44卷 / 06期
关键词：
INSULIN-RESISTANCE SYNDROME; IMPAIRED GLUCOSE-TOLERANCE; ENCODING ADIPONECTIN; METABOLIC SYNDROME; PROXIMAL PROMOTER; ASSOCIATION; RISK; CAUCASIANS; OBESITY; FAMILY;
D O I：
10.3103/S009545271006006X
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
+276G > T polymorphism in the adiponectine gene (APM1) was studied in 103 samples obtained from donors in the Kharkiv population (men/women: 64/38; 70 Ukrainian, 33 Russian). The T- and G-allele frequencies did not significantly differ between either men and women or between Russians and Ukrainians and comprised p(T) = 0.55 and p(G) = 0.45 in the general group. The genotype distribution deviated from the Hardy-Weinberg equilibrium: the heterozygote frequency was 1.55 times higher compared to the selectively neutral value, while the TT- and GG- homozygote frequencies were 0.55 and 0.33 of the equilibrium value, respectively.
引用
收藏
页码：361 / 364
页数：4
相关论文
共 50 条
  • [21] Adiponectin gene polymorphism (SNP276G>T) is associated with impaired glucose tolerance
    Huang, Meng-Chuan
    Wang, Tsu-Nai
    Wu, Yu-Ru
    Ko, Yin-Chin
    Brenna, J. Thomas
    FASEB JOURNAL, 2007, 21 (06): : A1053 - A1054
  • [22] Adiponectin gene polymorphism-276G>T contributes to arterial stiffness in essential hypertension
    Mahmud, A.
    Zhou, S.
    Feely, J.
    JOURNAL OF HYPERTENSION, 2007, 25 : S322 - S322
  • [23] The Association of Single Nucleotide Polymorphism -69T>G HSPA1A Gene with Bali Cattle Heat Tolerance
    Suhendro, I
    Jakaria, J.
    Priyanto, R.
    Manalu, W.
    Noor, R. R.
    TROPICAL ANIMAL SCIENCE JOURNAL, 2022, 45 (04) : 429 - 435
  • [24] Single Nucleotide Polymorphism at +276 G > T of the Adiponectin Gene and Plasma Adiponectin Level in Myanmar Type 2 Diabetic Patients
    Yu, Khin Thin
    Maung, Kyu Kyu
    Thida, Aye
    Myint, Thein
    JOURNAL OF THE ASEAN FEDERATION OF ENDOCRINE SOCIETIES, 2018, 33 (02): : 160 - 164
  • [25] Single nucleotide polymorphisms in the proximal promoter region of the adiponectin (APM1) gene are associated with type 2 diabetes in Swedish Caucasians
    Gu, HF
    Abulaiti, A
    Östenson, CG
    Humphreys, K
    Wahlestedt, C
    Brookes, AJ
    Efendic, S
    DIABETES, 2004, 53 : S31 - S35
  • [26] Interaction between PPARG Pro12Ala and APM1 G276T concerning cholesterol levels in childhood obesity
    Marcus, Claude
    Johansson, Lovisa
    Danielsson, Pernilla
    Norgren, Svante
    Sjogren, Marketa
    Ridderstale, Martin
    HORMONE RESEARCH, 2006, 65 : 19 - 19
  • [27] The myxovirus resistance A (MxA) gene-88G>T single nucleotide polymorphism is associated with prostate cancer
    Glymph, Shanora
    Mandal, Sanjay
    Knowell, Ashley Evans
    Abebe, Fisseha
    Chaudhary, Jaideep
    INFECTION GENETICS AND EVOLUTION, 2013, 16 : 186 - 190
  • [28] ADIPOQ gene (T45G and G276T) single nucleotide polymorphisms and their association with gestational diabetes mellitus in a Filipino population
    Larah Francesca A. Fernandez
    Maria Ruth B. Pineda-Cortel
    BMC Endocrine Disorders, 23
  • [29] ADIPOQ gene (T45G and G276T) single nucleotide polymorphisms and their association with gestational diabetes mellitus in a Filipino population
    Fernandez, Larah Francesca A.
    Pineda-Cortel, Maria Ruth B.
    BMC ENDOCRINE DISORDERS, 2023, 23 (01)
  • [30] SIRTUIN 1 GENE RS2273773 C > T SINGLE NUCLEOTIDE POLYMORPHISM IN ASTHMATIC PATIENTS
    Ali, Abdellah
    Abdeen, Aida
    RESPIROLOGY, 2015, 20 : 3 - 3
12345