Recent advances in cloning herpesviral genomes as infectious bacterial artificial chromosomes

被引：7
|
作者：
Zhou, Fuchun
Gao, Shou-Jiang [1 ]
机构：
[1] Univ Texas Hlth Sci Ctr San Antonio, Greehey Childrens Canc Res Inst, Tumor Virol Program, San Antonio, TX 78229 USA
来源：
CELL CYCLE | 2011年 / 10卷 / 03期
关键词：
herpesvirus; bacteria artificial chromosome; molecular cloning; reverse genetics; mutagenesis; VARICELLA-ZOSTER-VIRUS; TEMPERATURE-SENSITIVE MUTANTS; EPSTEIN-BARR-VIRUS; PHOSPHONOACETIC ACID-RESISTANT; COSMID-BASED SYSTEM; ESCHERICHIA-COLI; SIMPLEX-VIRUS; HUMAN CYTOMEGALOVIRUS; IN-VITRO; BACTERIOPHAGE-LAMBDA;
D O I：
10.4161/cc.10.3.14708
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Herpesviruses are common but important pathogens in humans and animals. These viruses have large complex genomes encoding genes with diverse functions in different phases of their life cycle and associated diseases. In the last decade, genomes of herpesviruses cloned as infectious bacterial artificial chromosomes (BACs) have become powerful tools for delineating the functions of viral genes and understanding the pathogenesis of their associated diseases. Here we review the history of herpesviral genetics and recent advances in methods for cloning herpesviral genomes as infectious BACs.
引用
收藏
页码：434 / 440
页数：7
相关论文
共 50 条
  • [41] YEAST ARTIFICIAL CHROMOSOMES - TOOLS FOR MAPPING AND ANALYSIS OF COMPLEX GENOMES
    SCHLESSINGER, D
    TRENDS IN GENETICS, 1990, 6 (08) : 248 - &
  • [42] Bacterial genomics: the use of DNA microarrays and bacterial artificial chromosomes
    Ball, KD
    Trevors, JT
    JOURNAL OF MICROBIOLOGICAL METHODS, 2002, 49 (03) : 275 - 284
  • [43] CLONING OF THE HUNTINGTON DISEASE REGION IN YEAST ARTIFICIAL CHROMOSOMES
    ZUO, J
    ROBBINS, C
    TAILLONMILLER, P
    COX, DR
    MYERS, RM
    HUMAN MOLECULAR GENETICS, 1992, 1 (03) : 149 - 159
  • [44] Press clippings - Comments on human cloning, artificial chromosomes
    不详
    BIOTECHNOLOGY LAW REPORT, 2000, 19 (02) : 168 - 168
  • [45] Carbon dots as a novel photosensitizer for photodynamic therapy of cancer and bacterial infectious diseases: recent advances
    Sun, Lingxiang
    Zhao, Yifan
    Peng, Hongyi
    Zhou, Jian
    Zhang, Qingmei
    Yan, Jingyu
    Liu, Yingyu
    Guo, Susu
    Wu, Xiuping
    Li, Bing
    JOURNAL OF NANOBIOTECHNOLOGY, 2024, 22 (01)
  • [46] Modified bacterial artificial chromosomes for zebrafish transgenesis
    Yang, Zhongan
    Jiang, Hong
    Chachainasakul, Thawinee
    Gong, Shiaoching
    Yang, Xiangdong William
    Heintz, Nathaniel
    Lin, Shuo
    METHODS, 2006, 39 (03) : 183 - 188
  • [47] Efficient cloning of plant genomes into bacterial artificial chromosome (BAC) libraries with larger and more uniform insert size
    Chalhoub, B
    Belcram, H
    Caboche, M
    PLANT BIOTECHNOLOGY JOURNAL, 2004, 2 (03) : 181 - 188
  • [48] Cloning the complete guinea pig cytomegalovirus genome as an infectious bacterial artificial chromosome with excisable origin of replication
    Cui, Xiaohong
    McGregor, Alistair
    Schleiss, Mark R.
    McVoy, Michael A.
    JOURNAL OF VIROLOGICAL METHODS, 2008, 149 (02) : 231 - 239
  • [49] Cloning of the Herpes smplex virus Type 1 genome as an novel luciferase infectious bacterial artificial chromosome
    You Li
    Shuai Wang
    Junji Xing
    Hua Zhu
    Chunfu Zheng
    BMC Proceedings, 5 (Suppl 1)
  • [50] Cloning human herpes virus 6A genome into bacterial artificial chromosomes and study of DNA replication intermediates
    Borenstein, Ronen
    Frenkel, Niza
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2009, 106 (45) : 19138 - 19143
12345