Some pharmacological effects of the ethanol extract of leaves of Annona diversifolia on the central nervous system in mice

被引：1
|
作者：
González-Trujano, ME
Navarrete, A [1 ]
Reyes, B
Hong, E
机构：
[1] Univ Nacl Autonoma Mexico, Fac Quim, Dept Farm, Mexico City 04510, DF, Mexico
[2] Univ Autonoma Chapingo, Are Quim, Lab Prod Nat, Mexico City 56230, DF, Mexico
[3] CINVESTAV, IPN, Secc Terapeut Expt, Dept Farmacol & Toxicol, Mexico City 14000, DF, Mexico
来源：
PHYTOTHERAPY RESEARCH | 1998年 / 12卷 / 08期
关键词：
Annona diversifolia; CNS activity; anticonvulsant; Mexican traditional medicine;
D O I：
10.1002/(SICI)1099-1573(199812)12:8<600::AID-PTR363>3.0.CO;2-N
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
In the present study we investigated some neuropharmacological effects of the ethanol extract of the leaves of Annona diversifolia (Annonaceae). Intraperitoneal administration of the extract delayed the onset of clonic seizures induced by pentylenetetrazole and delayed the time in the 'rota-rod' and 'swimming' test. In addition, the extract augmented the duration of sleeping time induced by sodium pentobarbital. These results indicate that the ethanol extract of the leaves of A. diversifolia has depressant activity on the central nervous system. (C) 1998 John Wiley & Sons, Ltd.
引用
收藏
页码：600 / 602
页数：3
相关论文
共 50 条
  • [21] The effects of the ethanol extract of Cordia myxa leaves on the cognitive function in mice
    Gülsen Kendir
    Ho Jung Bae
    Jihyun Kim
    Yongwoo Jeong
    Hyo Jeoung Bae
    Keontae Park
    Xingquan Yang
    Young-jin Cho
    Ji-Young Kim
    Seo Yun Jung
    Ayşegül Köroğlu
    Dae Sik Jang
    Jong Hoon Ryu
    BMC Complementary Medicine and Therapies, 22
  • [22] Effects of ethanol poisoning on the central nervous system.
    Feany, MB
    Zane, W
    Anthony, DC
    Frosch, MP
    De Girolami, U
    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 1998, 57 (05): : 487 - 487
  • [23] Cardenolides from the methanolic extract of Nerium oleander leaves possessing central nervous system depressant activity in mice
    Siddiqui, BS
    Sultana, R
    Begum, S
    Zia, A
    Suria, A
    JOURNAL OF NATURAL PRODUCTS, 1997, 60 (06): : 540 - 544
  • [24] CENTRAL-NERVOUS-SYSTEM EFFECTS OF ACETATE - CONTRIBUTION TO THE CENTRAL EFFECTS OF ETHANOL
    CARMICHAEL, FJ
    ISRAEL, Y
    CRAWFORD, M
    MINHAS, K
    SALDIVIA, V
    SANDRIN, S
    CAMPISI, P
    ORREGO, H
    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 1991, 259 (01): : 403 - 408
  • [25] Pharmacological evaluation of Potentilla alba L. in mice: adaptogenic and central nervous system effects
    Shikov, Alexander N.
    Lazukina, Maria A.
    Pozharitskaya, Olga N.
    Makarova, Marina N.
    Golubeva, Olga V.
    Makarov, Valery G.
    Djachuk, Georgy I.
    PHARMACEUTICAL BIOLOGY, 2011, 49 (10) : 1023 - 1028
  • [26] Pharmacological effects of primaquine ureas and semicarbazides on the central nervous system in mice and antimalarial activity in vitro
    Kedzierska, Ewa
    Orzelska, Jolanta
    Perkovic, Ivana
    Knezevic, Danijel
    Fidecka, Sylwia
    Kaiser, Marcel
    Zorc, Branka
    FUNDAMENTAL & CLINICAL PHARMACOLOGY, 2016, 30 (01) : 58 - 69
  • [27] Central nervous system activity of acute administration of ethanol extract of Punica granatum L. seeds in mice
    Kumar, Sokindra
    Maheshwari, Kamal Kishore
    Singh, Vijender
    INDIAN JOURNAL OF EXPERIMENTAL BIOLOGY, 2008, 46 (12) : 811 - 816
  • [28] Ethanol and amino acids in the central nervous system: assessment of the pharmacological actions of acamprosate
    Dahchour, A
    De Witte, P
    PROGRESS IN NEUROBIOLOGY, 2000, 60 (04) : 343 - 362
  • [29] Antiulcerogenic activity of the hydroalcoholic extract of leaves of Annona muricata Linnaeus in mice
    Bento, Elizangela Beneval
    de Brito Junior, Francisco Elizaudo
    de Oliveira, Dayanne Rakelly
    Fernandes, Cicera Norma
    Delmondes, Gyllyandeson de Aranjo
    Alves Santana Cesario, Francisco Rafael
    de Sousa Rodrigues, Cristina Kelly
    Sales, Valterlucio dos Santos
    Dantas Nobrega de Figueiredo, Francisco Rodolpho Sobreira
    Santiago Lemos, Izabel Cristina
    Monteiro, Alefe Brito
    Alencar de Menezes, Irwin Rose
    Martins da Costa, Jose Galberto
    Kerntopf, Marta Regina
    SAUDI JOURNAL OF BIOLOGICAL SCIENCES, 2018, 25 (04) : 609 - 621
  • [30] SOME EFFECTS OF BRADYKININ ON CENTRAL NERVOUS SYSTEM
    CAPEK, R
    BIOCHEMICAL PHARMACOLOGY, 1962, 10 (OCT) : 61 - +
12345