Phase II study of a human anti-interleukin (IL)-12/IL-23 monoclonal antibody in the treatment of psoriasis

被引：0
|
作者：
Langely, RG
Lebwohl, M
Leonardi, C
Yeilding, N
Guzzo, C
Wang, Y
Dooley, L
Krueger, GG
机构：
[1] Dalhousie Univ, Halifax, NS B3H 3J5, Canada
[2] Mt Sinai Sch Med, New York, NY USA
[3] St Louis Univ, St Louis, MO 63103 USA
[4] Centocor Inc, Malvern, PA 19355 USA
[5] Univ Utah, Hlth Sci Ctr, Salt Lake City, UT 84112 USA
来源：
JOURNAL OF INVESTIGATIVE DERMATOLOGY | 2005年 / 125卷 / 03期
关键词：
D O I：
暂无
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
407
引用
收藏
页码：A69 / A69
页数：1
相关论文
共 50 条
  • [41] Risk of tuberculosis reactivation with interleukin (IL)-17 and IL-23 inhibitors in psoriasis - time for a paradigm change
    Nogueira, M.
    Warren, R. B.
    Torres, T.
    JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, 2021, 35 (04) : 824 - 834
  • [42] A phase II study of STA-5326, an oral IL-12 and IL-23 inhibitor, in patients with moderate-to-severe chronic plaque psoriasis (CPP)
    Gordon, K
    Tschen, E
    Korman, N
    Cather, J
    Gold, M
    Hampel, F
    Miller, S
    Jacobson, E
    Sherman, M
    BRITISH JOURNAL OF DERMATOLOGY, 2006, 154 (01)
  • [43] Safety and efficacy of the fully human IL-12/-23 monoclonal antibody, ABT-874, in the treatment of moderate to severe plaque psoriasis: Results from a Phase II trial
    Kimball, A. B.
    Gordon, K. B.
    Valdes, J. M.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2007, 127 : S54 - S54
  • [44] Risankizumab.rzaa: an interleukin monoclonal antibody antagonist binding to the p19 subunit of human IL-23 cytokine
    Paton, D. M.
    DRUGS OF TODAY, 2019, 55 (10) : 605 - 613
  • [45] Responses to Leishmania donovani in mice deficient in interleukin-12 (IL-12), IL-12/IL-23, or IL-18
    Murray, Henry W.
    Tsai, Christine W.
    Liu, Jianguo
    Ma, Xiaojing
    INFECTION AND IMMUNITY, 2006, 74 (07) : 4370 - 4374
  • [46] Monoclonal antibodies inhibiting IL-12,-23, and-17 for the treatment of psoriasis
    Jeon, Caleb
    Sekhon, Sahil
    Yan, Di
    Afifi, Ladan
    Nakamura, Mio
    Bhutani, Tina
    HUMAN VACCINES & IMMUNOTHERAPEUTICS, 2017, 13 (10) : 2247 - 2259
  • [47] Evaluation of interleukin-23 receptor (IL-23R) gene polymorphisms and serum IL-23 levels in patients with psoriasis
    Filiz, Basak
    Yildirim, Mehmet
    Hekimler Ozturk, Kuyas
    Sirin, Fevziye Burcu
    Celik, Seda
    Erturan, Ijlal
    Korkmaz, Selma
    Orhan, Hikmet
    TURKISH JOURNAL OF MEDICAL SCIENCES, 2019, 49 (05) : 1386 - 1394
  • [48] Use of anti-interleukin 6 receptor monoclonal antibody for the treatment of Endometriosis
    Abou-EL-Naga, Amoura M.
    El-Zayadi, Ahmed A.
    Tag, Yasmin M.
    Fawzy, Nada M.
    BIOSCIENCE RESEARCH, 2022, 19 (02): : 836 - 843
  • [49] Human anti-interleukin IL-12/IL-23 p40 mAb (CNTO1275) inhibits IL-12-induced expression of skin homing molecule, cutaneous lymphocyte antigen and IL-12 receptors on activated peripheral blood T lymphocytes
    Reddy, MP
    Davis, C
    Wong, J
    Pendley, C
    Prabhakar, U
    BRITISH JOURNAL OF DERMATOLOGY, 2006, 154 (01)
  • [50] Why did IL-12/IL-23 antibody therapy fail in multiple sclerosis?
    Longbrake, Erin E.
    Racke, Michael K.
    EXPERT REVIEW OF NEUROTHERAPEUTICS, 2009, 9 (03) : 319 - 321
12345