Mutations of BRAF and BIRC3 Identify a Subgroup of Chronic Lymphocytic Leukemia with Very Poor Prognosis upon FCR Treatment

被引：0

作者：

Moia, Riccardo ^{[1
]}

Diop, Fary ^{[1
]}

Favini, Chiara ^{[1
]}

Spaccarotella, Elisa ^{[1
]}

De Paoli, Lorenzo ^{[1
]}

Bruscaggin, Alessio ^{[2
]}

Spina, Valeria ^{[2
]}

Cerri, Michaela

Deambrogi, Clara ^{[1
]}

Kodipad, Ahad Ahmed ^{[1
]}

Favini, Simone ^{[1
]}

Sagiraju, Sruthi ^{[1
]}

Jabangwe, Clive ^{[1
]}

Mauro, Francesca Romana ^{[3
]}

Del Giudice, Ilaria ^{[3
]}

Forconi, Francesco ^{[4
,5
,6
]}

Cortelezzi, Agostino ^{[7
,8
]}

Zaja, Francesco ^{[9
]}

Visco, Carlo ^{[10
]}

Chiarenza, Annalisa ^{[11
]}

Rigolin, Gian Matteo ^{[12
]}

Marasca, Roberto ^{[13
]}

Coscia, Marta ^{[14
,15
]}

Perbellini, Omar ^{[16
]}

Tedeschi, Alessandra ^{[17
]}

Laurenti, Luca ^{[18
]}

Motta, Marina ^{[19
]}

Del Poeta, Giovanni ^{[20
]}

Cuneo, Antonio ^{[12
]}

Gattei, Valter ^{[21
]}

Foa, Robin ^{[3
]}

Gaidano, Gianluca ^{[1
]}

Rossi, Davide ^{[2
]}

机构：

[1] Amedeo Avogadro Univ Eastern Piedmont, Dept Translat Med, Div Hematol, Novara, Italy

[2] Inst Southern Switzerland, Inst Oncol Res & Oncol, Bellinzona, Switzerland

[3] Sapienza Univ, Dept Cellular Biotechnol & Hematol, Hematol, Rome, Italy

[4] Univ Southampton, Southampton Canc Res UK, Canc Sci Unit, Southampton, Hants, England

[5] Univ Southampton, Natl Inst Hlth Res, Expt Canc Med Ctr, Southampton, Hants, England

[6] Univ Siena, Div Hematol, Siena, Italy

[7] Fdn IRCCS Ca Granda Osped Maggiore Policlin, Dept Hematol Oncol, Milan, Italy

[8] Univ Milan, Milan, Italy

[9] Univ Udine, DAME, Clin Ematol, Udine, Italy

[10] Osped San Bortolo, Dept Cell Therapy & Hematol, Vicenza, Italy

[11] Azienda Osped Univ Policlin OVE, Div Hematol, Catania, Italy

[12] Univ Ferrara, Azienda Osped Univ Arcispedale S Anna, Hematol Sect, Ferrara, Italy

[13] Univ Modena & Reggio Emilia, Dept Hematol & Oncol, Div Hematol, Modena, Italy

[14] Azienda Ospedaliero Univ Citta Salute & Sci, Div Hematol, Turin, Italy

[15] Univ Turin, Turin, Italy

[16] Univ Verona, Dept Med, Sect Hematol, Verona, Italy

[17] Osped Niguarda Ca Granda, Niguarda Canc Ctr, Dept Oncol Haematol, Milan, Italy

[18] Univ Cattolica Sacro Cuore, Inst Hematol, Rome, Italy

[19] Spedali Civil Brescia, Dept Hematol, Brescia, Italy

[20] Tor Vergata Univ, Dept Hematol, Rome, Italy

[21] IRCCS, Ctr Riferimento Oncol, Clin & Expt Oncohematol Unit, Aviano, Italy

来源：

CLINICAL LYMPHOMA MYELOMA & LEUKEMIA | 2017年 / 17卷 / 10期

关键词：

chronic lymphocytic leukemia; FCR; immunochemotherapy; molecular predictors; precision medicine;

D O I：

10.1016/j.clml.2017.09.039

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

CLL-009

引用

页码：S11 / S12

页数：2

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