Effects of corticosterone on connectin content and protein breakdown in rat skeletal muscle

被引：14
|
作者：
Hayashi, K [1 ]
Tada, O [1 ]
Higuchi, K [1 ]
Ohtsuka, A [1 ]
机构：
[1] Kagoshima Univ, Fac Agr, Dept Biochem Sci & Technol, Kagoshima 8900065, Japan
来源：
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 2000年 / 64卷 / 12期
关键词：
connectin; corticosterone; calpain; muscle protein breakdown;
D O I：
10.1271/bbb.64.2686
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
We examined the effects of a glucocorticoid, corticosterone, on calpain activity, connectin content and protein breakdown in rat muscle. The results indicated that calpain activity was increased by corticosterone and thus breakdown of connectin was stimulated followed by increased breakdown of skeletal muscle protein.
引用
收藏
页码：2686 / 2688
页数：3
相关论文
共 50 条
  • [31] Effects of voluntary wheel running on mitochondrial content and dynamics in rat skeletal muscle
    Barnaby P. Frankish
    Petra Najdovska
    Hongyang Xu
    Stefan G. Wette
    Robyn M. Murphy
    Journal of Muscle Research and Cell Motility, 2021, 42 : 67 - 76
  • [32] Effects of thyroid hormone on protein synthesis in rat skeletal muscle.
    Pohnert, SC
    Fluckey, JD
    Lang, MC
    Boyd, SG
    Dohm, GL
    FASEB JOURNAL, 1998, 12 (04): : A430 - A430
  • [33] CORTICOSTERONE AND MUSCLE PROTEIN BREAKDOWN INVIVO IN RATS - EFFECT OF SUBCUTANEOUS AND INTRAPERITONEAL INJECTION
    SANTIDRIAN, S
    YOUNG, VR
    REVISTA ESPANOLA DE FISIOLOGIA, 1980, 36 (01): : 93 - 94
  • [34] Aging skeletal muscle mitochondria in the rat: decreased uncoupling protein-3 content
    Kerner, J
    Turkaly, PJ
    Minkler, PE
    Hoppel, CL
    AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2001, 281 (05): : E1054 - E1062
  • [35] PROTEIN AND COLLAGEN CONTENT OF RAT SKELETAL-MUSCLE FOLLOWING SPACE-FLIGHT
    MARTIN, TP
    CELL AND TISSUE RESEARCH, 1988, 254 (01) : 251 - 253
  • [36] TIME COURSE OF THE EFFECT OF CATABOLIC DOSES OF CORTICOSTERONE ON PROTEIN-TURNOVER IN RAT SKELETAL-MUSCLE AND LIVER
    ODEDRA, BR
    BATES, PC
    MILLWARD, DJ
    BIOCHEMICAL JOURNAL, 1983, 214 (02) : 617 - 627
  • [37] Calpain and connectin/titin in health and disease of skeletal muscle.
    Sorimachi, H
    Ono, Y
    Ojima, K
    Kawabata, Y
    Witt, C
    Nakano, H
    Kawahara, H
    Hata, S
    Koyama, S
    Granzier, H
    Gregorio, CC
    Labeit, S
    Aiba, A
    Abe, K
    Suzuki, K
    FEBS JOURNAL, 2005, 272 : 177 - +
  • [38] EFFECTS OF DIETARY CORTICOSTERONE AND TRILOSTANE ON GROWTH AND SKELETAL-MUSCLE PROTEIN-TURNOVER IN BROILER COCKERELS
    HAYASHI, K
    NAGAI, Y
    OHTSUKA, A
    TOMITA, Y
    BRITISH POULTRY SCIENCE, 1994, 35 (05) : 789 - 798
  • [39] CONNECTIN, AN ELASTIC PROTEIN OF STRIATED-MUSCLE
    MARUYAMA, K
    BIOPHYSICAL CHEMISTRY, 1994, 50 (1-2) : 73 - 85
  • [40] Connectin/titin, giant elastic protein of muscle
    Maruyama, K
    FASEB JOURNAL, 1997, 11 (05): : 341 - 345
12345