Interactions between Innate Lymphoid Cells and Cells of the Innate and Adaptive Immune System

被引:38
|
作者
Symowski, Cornelia
Voehringer, David [1 ]
机构
[1] Univ Hosp Erlangen, Dept Infect Biol, Erlangen, Germany
来源
FRONTIERS IN IMMUNOLOGY | 2017年 / 8卷
关键词
allergic inflammation; helminths; mast cells; innate lymphoid cells; eosinophils; basophils; Th2; cells; alternatively activated macrophages; ALTERNATIVELY ACTIVATED MACROPHAGES; NATURAL HELPER-CELLS; LUNG INFLAMMATION; TYPE-2; IMMUNITY; AIRWAY INFLAMMATION; IL-33; PROMOTES; RESPONSES; EOSINOPHILS; EXPRESSION;
D O I
10.3389/fimmu.2017.01422
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Type 2 innate lymphoid cells (ILC2s) are a major source of cytokines, which are also produced by Th2 cells and several cell types of the innate immune system. Work over the past few years indicates that ILC2s play a central role in regulating type 2 immune responses against allergens and helminths. ILC2s can interact with a variety of cells types of the innate and adaptive immune system by cell-cell contacts or by communication via soluble factors. In this review, we provide an overview about recent advances in our understanding how ILC2s orchestrate type 2 immune responses with focus on direct interactions between ILC2s and other cells of the immune system.
引用
收藏
页数:8
相关论文
共 50 条
  • [1] Regulation of the adaptive immune system by innate lymphoid cells
    Hepworth, Matthew R.
    Sonnenberg, Gregory F.
    [J]. CURRENT OPINION IN IMMUNOLOGY, 2014, 27 : 75 - 82
  • [2] Functional interactions between innate lymphoid cells and adaptive immunity
    Sonnenberg, Gregory E.
    Hepworth, Matthew R.
    [J]. NATURE REVIEWS IMMUNOLOGY, 2019, 19 (10) : 599 - 613
  • [3] Functional interactions between innate lymphoid cells and adaptive immunity
    Gregory F. Sonnenberg
    Matthew R. Hepworth
    [J]. Nature Reviews Immunology, 2019, 19 : 599 - 613
  • [4] Innate lymphoid cells at the crossroads of innate and adaptive immunity
    Korangy, Firouzeh
    Heinrich, Bernd
    Greten, Tim F.
    [J]. HEPATOLOGY, 2022, 76 (04) : 903 - 905
  • [5] Interactions between the intestinal microbiota and innate lymphoid cells
    Chen, Vincent L.
    Kasper, Dennis L.
    [J]. GUT MICROBES, 2014, 5 (01) : 129 - 140
  • [6] The roles for innate lymphoid cells in the human immune system
    Mazzurana, L.
    Rao, A.
    Van Acker, A.
    Mjosberg, J.
    [J]. SEMINARS IN IMMUNOPATHOLOGY, 2018, 40 (04) : 407 - 419
  • [7] The roles for innate lymphoid cells in the human immune system
    L. Mazzurana
    A. Rao
    A. Van Acker
    J. Mjösberg
    [J]. Seminars in Immunopathology, 2018, 40 : 407 - 419
  • [8] Neural Regulation of Interactions Between Group 2 Innate Lymphoid Cells and Pulmonary Immune Cells
    Chen, Weiwei
    Shu, Qiang
    Fan, Jie
    [J]. FRONTIERS IN IMMUNOLOGY, 2020, 11
  • [9] Investigating the role of innate lymphoid cells in adaptive immune responses
    Mackley, E. C.
    Marriott, C. L.
    McConnell, F. M.
    Toellner, K. M.
    Anderson, G.
    Lane, P. J.
    Withers, D. R.
    [J]. IMMUNOLOGY, 2013, 140 : 94 - 94
  • [10] Innate Immune Sensing by Cells of the Adaptive Immune System
    Stogerer, Tanja
    Stager, Simona
    [J]. FRONTIERS IN IMMUNOLOGY, 2020, 11