Facile Knoevenagel and Domino Knoevenagel/Michael Reactions Using Gel-Entrapped Base Catalysts

被引：13
|
作者：
Shinde, Shital [1 ]
Rashinkar, Gajanan [1 ]
Kumbhar, Arjun [1 ]
Kamble, Santosh [1 ]
Salunkhe, Rajashri [1 ]
机构：
[1] Shivaji Univ, Dept Chem, Kolhapur 416004, Maharashtra, India
来源：
HELVETICA CHIMICA ACTA | 2011年 / 94卷 / 11期
关键词：
Knoevenagel condensation; Michael reaction; Gel-entrapped base catalysts; Recyclability; Methylene compounds; Catalysis; SOLVENT-FREE SYNTHESIS; POTASSIUM FLUORIDE; CONDENSATION; TETRAKETONES;
D O I：
10.1002/hlca.201100133
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An efficient method for Knoevenagel condensation of arenecarbaldehydes with active methylene compounds such as barbituric acid and Meldrum's acid in the presence of gel-entrapped base catalysts is reported. The method has been extended to the one-pot synthesis of arylmethylene-bis[3-hydroxycyclohex-2-en-1-one] derivatives from dimedone (=5,5-dimethylcyclohexane-1,3-dione) and arenecarbaldehydes by using domino Knoevenagel/Michael reaction sequence.
引用
收藏
页码：1943 / 1951
页数：9
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