Efficacy of the novel fungal Cyp51 inhibitor VT-1161 against invasive candidiasis caused by resistant Candida albicans

被引:0
|
作者
Najvar, L. K. [1 ,2 ]
Wiederhold, N. P. [1 ,3 ]
Garvey, E. P. [4 ]
Hoekstra, W. J. [4 ]
Moore, W. R. [4 ]
Schotzinger, R. J. [4 ]
Bocanegra, R. A. [1 ,2 ]
Kirkpatrick, W. R. [1 ,2 ]
Patterson, T. F. [1 ,2 ]
机构
[1] UTHSCSA, San Antonio, TX USA
[2] STVHCS, San Antonio, TX USA
[3] UT Austin, Austin, TX USA
[4] Viamet Pharmaceut Inc, Morrisville, NC USA
关键词
D O I
暂无
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
引用
收藏
页码:106 / 106
页数:1
相关论文
共 45 条
  • [41] Oral glucan synthase inhibitor SCY-078 is effective in an experimental murine model of invasive candidiasis caused by WT and echinocandin-resistant Candida glabrata
    Wiederhold, Nathan P.
    Najvar, Laura K.
    Jaramillo, Rosie
    Olivo, Marcos
    Pizzini, Jason
    Catano, Gabriel
    Patterson, Thomas F.
    [J]. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2018, 73 (02) : 448 - 451
  • [42] Ibrexafungerp Demonstrates In Vitro Activity against Fluconazole-Resistant Candida auris and In Vivo Efficacy with Delayed Initiation of Therapy in an Experimental Model of Invasive Candidiasis
    Wiederhold, Nathan P.
    Najvar, Laura K.
    Olivo, Marcos
    Morris, Kelsey N.
    Patterson, Hoja P.
    Catano, Gabriel
    Patterson, Thomas F.
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2021, 65 (06)
  • [43] Seconeolitsine, the Novel Inhibitor of DNA Topoisomerase I, Protects against Invasive Pneumococcal Disease Caused by Fluoroquinolone-Resistant Strains
    Tirado-Velez, Jose Manuel
    Carreno, David
    Sevillano, David
    Alou, Luis
    Yuste, Jose
    de la Campa, Adela G.
    [J]. ANTIBIOTICS-BASEL, 2021, 10 (05):
  • [44] Significantly Improved Pharmacokinetics Enhances In Vivo Efficacy of APX001 against Echinocandin- and Multidrug-Resistant Candida Isolates in a Mouse Model of Invasive Candidiasis
    Zhao, Yanan
    Lee, Min Hee
    Paderu, Padmaja
    Lee, Annie
    Jimenez-Ortigosa, Cristina
    Park, Steven
    Mansbach, Robert S.
    Shaw, Karen Joy
    Perlin, David S.
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2018, 62 (10)
  • [45] Combination of Six Individual Derivatives of the Pom-1 Antibiofilm Peptide Doubles Their Efficacy against Invasive and Multi-Resistant Clinical Isolates of the Pathogenic Yeast Candida albicans
    Haering, Michelle
    Amann, Valerie
    Kissmann, Ann-Kathrin
    Herberger, Tilmann
    Synatschke, Christopher
    Kirsch-Pietz, Nicole
    Perez-Erviti, Julio A.
    Otero-Gonzalez, Anselmo J.
    Morales-Vicente, Fidel
    Andersson, Jakob
    Weil, Tanja
    Stenger, Steffen
    Rodriguez, Armando
    Staendker, Ludger
    Rosenau, Frank
    [J]. PHARMACEUTICS, 2022, 14 (07)