An axisymmetric flow-focusing microfluidic device

被引:309
|
作者
Takeuchi, S
Garstecki, P
Weibel, DB
Whitesides, GM
机构
[1] Harvard Univ, Dept Chem & Biol Chem, Cambridge, MA 02138 USA
[2] Univ Tokyo, Inst Ind Sci, Meguro Ku, Tokyo 1538505, Japan
关键词
D O I
10.1002/adma.200401738
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
An axisymmetric flow-focusing microfluidic device (AFFD) is described. The AFFD (see Figure, top) produces micrometer-sized (50-300 mu m) polymercoated droplets (see Figure, bottom) with narrow size distributions (< 5%). The axisymmetric geometry confines droplets to the central axis of the channel and prevents them from being sheared or damaged at the channel walls. The device is used to prepare aqueous droplets encapsulated in nylon-6,6 membranes by carrying out interfacial polymerization reactions in situ.
引用
收藏
页码:1067 / +
页数:7
相关论文
共 50 条
  • [1] Simulation of a microfluidic flow-focusing device
    Dupin, Michael M.
    Halliday, Ian
    Care, Chris M.
    [J]. PHYSICAL REVIEW E, 2006, 73 (05):
  • [2] Formation of monodisperse bubbles in a microfluidic flow-focusing device
    Garstecki, P
    Gitlin, I
    DiLuzio, W
    Whitesides, GM
    Kumacheva, E
    Stone, HA
    [J]. APPLIED PHYSICS LETTERS, 2004, 85 (13) : 2649 - 2651
  • [3] A hybrid axisymmetric flow-focusing device for monodisperse picoliter droplets
    Morimoto, Yuya
    Kuribayashi-Shigetomi, Kaori
    Takeuchi, Shoji
    [J]. JOURNAL OF MICROMECHANICS AND MICROENGINEERING, 2011, 21 (05)
  • [4] A computational study of drop formation in an axisymmetric flow-focusing device
    Filiz, Ismail
    Muradoglu, Metin
    [J]. PROCEEDINGS OF THE 4TH INTERNATIONAL CONFERENCE ON NANOCHANNELS, MICROCHANNNELS, AND MINICHANNELS, PTS A AND B, 2006, : 1067 - 1074
  • [5] Characterization of acoustic droplet formation in a microfluidic flow-focusing device
    Cheung, Yin Nee
    Qiu, Huihe
    [J]. PHYSICAL REVIEW E, 2011, 84 (06):
  • [6] Bubble formation and breakup mechanism in a microfluidic flow-focusing device
    Fu, Taotao
    Ma, Youguang
    Funfschilling, Denis
    Li, Huai Z.
    [J]. CHEMICAL ENGINEERING SCIENCE, 2009, 64 (10) : 2392 - 2400
  • [7] Emulsification in a microfluidic flow-focusing device: effect of the viscosities of the liquids
    Zhihong Nie
    MinsSeok Seo
    Shengqing Xu
    Patrick C. Lewis
    Michelle Mok
    Eugenia Kumacheva
    George M. Whitesides
    Piotr Garstecki
    Howard A. Stone
    [J]. Microfluidics and Nanofluidics, 2008, 5 : 585 - 594
  • [8] Emulsification in a microfluidic flow-focusing device: effect of the viscosities of the liquids
    Nie, Zhihong
    Seo, MinsSeok
    Xu, Shengqing
    Lewis, Patrick C.
    Mok, Michelle
    Kumacheva, Eugenia
    Whitesides, George M.
    Garstecki, Piotr
    Stone, Howard A.
    [J]. MICROFLUIDICS AND NANOFLUIDICS, 2008, 5 (05) : 585 - 594
  • [9] Parametric study of droplet size in an axisymmetric flow-focusing capillary device
    Mostafa Rahimi
    Sajad Yazdanparast
    Pouya Rezai
    [J]. Chinese Journal of Chemical Engineering, 2020, 28 (04) : 1016 - 1022
  • [10] Three-dimensional axisymmetric flow-focusing device using stereolithography
    Morimoto, Yuya
    Tan, Wei-Heong
    Takeuchi, Shoji
    [J]. BIOMEDICAL MICRODEVICES, 2009, 11 (02) : 369 - 377