Reaction of Ethyl 5-Acetyl-3,4-dihydropyridine-1(2H)-carboxylate with 1,3-N,N-Bis-nucleophiles: A Facile Access to Novel Pyrimidine Derivatives

被引：5

作者：

Maximov, Nazar B. ^{[1
,2
]}

Mykhailiuk, Pavel K. ^{[1
,2
]}

Kisel, Andrei I. ^{[2
]}

Voitenko, Zoia V. ^{[2
]}

Tolmachev, Andrey A. ^{[1
,2
]}

机构：

[1] Enamine Ltd, UA-01103 Kiev, Ukraine

[2] Kiev Natl Taras Shevchenko Univ, Dept Chem, UA-01033 Kiev, Ukraine

来源：

SYNTHESIS-STUTTGART | 2011年 / 09期

关键词：

pyrimidines; amidines; amino heterocycles; tetrahydropyridine; HALOACETYLATED ENOL ETHERS; HYDRAZINES;

D O I：

10.1055/s-0030-1259970

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reaction of ethyl 5-acetyl-3,4-dihydropyridine-1(2H)-carboxylate with diverse 1,3-N,N-bis-nucleophiles results in the regioselective formation of the correspondingly substituted pyrimidines in good yields.

引用

页码：1465 / 1471

页数：7

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