Reaction of Ethyl 5-Acetyl-3,4-dihydropyridine-1(2H)-carboxylate with 1,3-N,N-Bis-nucleophiles: A Facile Access to Novel Pyrimidine Derivatives

被引：5
|
作者：
Maximov, Nazar B. [1 ,2 ]
Mykhailiuk, Pavel K. [1 ,2 ]
Kisel, Andrei I. [2 ]
Voitenko, Zoia V. [2 ]
Tolmachev, Andrey A. [1 ,2 ]
机构：
[1] Enamine Ltd, UA-01103 Kiev, Ukraine
[2] Kiev Natl Taras Shevchenko Univ, Dept Chem, UA-01033 Kiev, Ukraine
来源：
SYNTHESIS-STUTTGART | 2011年 / 09期
关键词：
pyrimidines; amidines; amino heterocycles; tetrahydropyridine; HALOACETYLATED ENOL ETHERS; HYDRAZINES;
D O I：
10.1055/s-0030-1259970
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Reaction of ethyl 5-acetyl-3,4-dihydropyridine-1(2H)-carboxylate with diverse 1,3-N,N-bis-nucleophiles results in the regioselective formation of the correspondingly substituted pyrimidines in good yields.
引用
收藏
页码：1465 / 1471
页数：7
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