Organic boronic acids and boronic acid esters in industrial synthesis

The Suzuki reaction is today one of the most common cross-coupling methods in modem organic synthesis. This importance is due in particular to widespread industrial use for the production of complex specialty chemicals, such as building blocks for active pharmaceutical ingredients, electronic materials or high performance metallocene catalysts. The immediate prerequisite for this development is in turn the availability of organic boronic acids and boronic acid esters in quantities of several hundred kilograms, which sometimes have to be produced at temperatures down to -100degreesC Siemens Axiva offers the requisite technical equipment for this purpose and more than ten years of experience for customers from the chemical and pharmaceutical industries.