Involvement of the p16INK4 (CDKN2) gene in familial melanoma

被引：7
|
作者：
Naylor, MF
Everett, MA
机构：
[1] Department of Dermatology, Center for Molecular Medicine, Univ. of Oklahoma Hlth. Sci. Center, Oklahoma City, OK 73190
来源：
MELANOMA RESEARCH | 1996年 / 6卷 / 02期
关键词：
CDKN2; cell cycle; cyclin-dependent kinase inhibitors; familial melanoma; p16INK4; tumor suppressors;
D O I：
10.1097/00008390-199604000-00009
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Recent work on the molecular genetics of familial melanoma has suggested that the pie kinase inhibitor gene (CDKN2) is one of the genes causing familial melanoma. Evidence for the candidacy of the pie gene as a familial melanoma gene is summarized and the characteristics of this class of cell cycle control proteins are reviewed.
引用
收藏
页码：139 / 145
页数：7
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