p16INK4/CDKN2在胆囊癌中的表达及临床意义

[1] Multiple mechanisms ofp16INK4A inactivation in non-small cell lungcancer lines. Geoffrey I Shapire,Julie E Park,Christian DEdwards et al. Cancer Research . 1995

[2] A newregulatory motif in cell-cycle control causingspecific inhibition of cyc1in D/CDK4. Serrano M,Hannon G J,Beach D A. Nature . 1993

[3] YoshihitoIchikawa et al.Mutations of p16INK4/CDKN2and p15INK4B/MTS2 genes in biliary tractcancer. Sadao Yoshida,Takeshi Todroki. Cancer Research . 1995

[4] Loss of thep16/cyclin-dependent kinase inhibitor 2 tumor.suppressor gene in melanocytic lesion correlateswith invasive stage of tumor progression. Jon A,Frank,Loganzo Jr et al. CanRes . 1995

[5] Homozygous deletions of the mu1tiple tumorsuppressor gene 1 in the progression of humanastrocytomas. David G Walker,Wei Duan,Ernil A Popvic etal. Cancer Research . 1995

[6] Kratzke et al- Im-munohistochemical detection of the cyclin-de-pendent kinase inhibitor 2/multiPle tumor sup-pressor gene 1 (CDKN2/MTS1) productp16INK4 in archival human solid tumors: corre-lation with retionblastoma protein expression. Joseph Geradts,Robert A. Cancer Research . 1995

[7] ln-creased p16 levels correlate with pRB alter-ations in human urothelial cells. Thomas Y,Walter S,Cassandra B et al. Cancer Research . 1995

[1] Multiple mechanisms ofp16INK4A inactivation in non-small cell lungcancer lines. Geoffrey I Shapire,Julie E Park,Christian DEdwards et al. Cancer Research . 1995

[2] A newregulatory motif in cell-cycle control causingspecific inhibition of cyc1in D/CDK4. Serrano M,Hannon G J,Beach D A. Nature . 1993

[3] YoshihitoIchikawa et al.Mutations of p16INK4/CDKN2and p15INK4B/MTS2 genes in biliary tractcancer. Sadao Yoshida,Takeshi Todroki. Cancer Research . 1995

[4] Loss of thep16/cyclin-dependent kinase inhibitor 2 tumor.suppressor gene in melanocytic lesion correlateswith invasive stage of tumor progression. Jon A,Frank,Loganzo Jr et al. CanRes . 1995

[5] Homozygous deletions of the mu1tiple tumorsuppressor gene 1 in the progression of humanastrocytomas. David G Walker,Wei Duan,Ernil A Popvic etal. Cancer Research . 1995

[6] Kratzke et al- Im-munohistochemical detection of the cyclin-de-pendent kinase inhibitor 2/multiPle tumor sup-pressor gene 1 (CDKN2/MTS1) productp16INK4 in archival human solid tumors: corre-lation with retionblastoma protein expression. Joseph Geradts,Robert A. Cancer Research . 1995

[7] ln-creased p16 levels correlate with pRB alter-ations in human urothelial cells. Thomas Y,Walter S,Cassandra B et al. Cancer Research . 1995