Area IV Knockout Reveals How Pdx1 Is Regulated in Postnatal β-Cell Development

被引：6
|
作者：
Cox, Aaron R. [1 ]
Kushner, Jake A. [1 ]
机构：
[1] Texas Childrens Hosp, Baylor Coll Med, McNair Med Inst, Houston, TX 77030 USA
来源：
DIABETES | 2017年 / 66卷 / 11期
基金：
美国国家卫生研究院;
关键词：
NUCLEAR FACTOR 3-BETA; TRANSCRIPTION FACTOR; GENE; EXPRESSION; PANCREAS; REGION; MICE; MATURATION;
D O I：
10.2337/dbi17-0036
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：2738 / 2740
页数：3
相关论文
共 50 条
  • [31] Context-specific α-to-β-cell reprogramming by forced Pdx1 expression
    Yang, Yu-Ping
    Thorel, Fabrizio
    Boyer, Daniel F.
    Herrera, Pedro L.
    Wright, Christopher V. E.
    GENES & DEVELOPMENT, 2011, 25 (16) : 1680 - 1685
  • [32] Chronic hyperglycemia induced via the heterozygous knockout of Pdx1 worsens neuropathological lesion in an Alzheimer mouse model
    Guo, Chuang
    Zhang, Shuai
    Li, Jia-Yi
    Ding, Chen
    Yang, Zhao-Hui
    Chai, Rui
    Wang, Xu
    Wang, Zhan-You
    SCIENTIFIC REPORTS, 2016, 6
  • [33] Cooperative function of Pdx1 and Oc1 in multipotent pancreatic progenitors impacts postnatal islet maturation and adaptability
    Kropp, Peter A.
    Dunn, Jennifer C.
    Carboneau, Bethany A.
    Stoffers, Doris A.
    Gannon, Maureen
    AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2018, 314 (04): : E308 - E321
  • [34] Chronic hyperglycemia induced via the heterozygous knockout of Pdx1 worsens neuropathological lesion in an Alzheimer mouse model
    Chuang Guo
    Shuai Zhang
    Jia-Yi Li
    Chen Ding
    Zhao-Hui Yang
    Rui Chai
    Xu Wang
    Zhan-You Wang
    Scientific Reports, 6
  • [35] Regulation of postnatal pancreatic Pdx1 and downstream target genes after gestational exposure to protein restriction in rats
    Abuzgaia, Awatif M.
    Hardy, Daniel B.
    Arany, Edith
    REPRODUCTION, 2015, 149 (03) : 293 - 303
  • [36] MST1 mediates beta cell failure by targeting BIM and destabilising PDX1
    Ardestani, A.
    Paroni, F.
    Kerr-Conte, J.
    Maedler, K.
    DIABETOLOGIA, 2012, 55 : S218 - S218
  • [37] Analysis of the Arabidopsis rsr4-1/pdx1-3 mutant reveals the critical function of the PDX1 protein family in metabolism, development, and vitamin B6 biosynthesis
    Wagner, Susan
    Bernhardt, Anne
    Leuendorf, Jan Erik
    Drewke, Christel
    Lytovchenko, Anna
    Mujahed, Nader
    Gurgui, Cristian
    Frommer, Wolf B.
    Leistner, Eckhard
    Fernie, Alisdair R.
    Hellmann, Hanjo
    PLANT CELL, 2006, 18 (07): : 1722 - 1735
  • [38] Hnf6 and Pdx1 Occupy Common Targets During Pancreas Development
    Stanescu, Diana E.
    Raum, Jeffrey C.
    Stoffers, Doris A.
    DIABETES, 2013, 62 : A11 - A11
  • [39] KEY REGULATOR OF PANCREATIC DEVELOPMENT PDX1 INCREASES CELL ADHESION AND REDUCES METASTATIC POTENTIAL OF PANCREATIC CANCER CELLS
    Kondratyeva, Liya
    Chernov, Igor
    Sverdlov, Eugene
    TISSUE ENGINEERING PART A, 2022, 28 : S71 - S71
  • [40] Pdx1 expression in Irs2-deficient mouse β-cells is regulated in a strain-dependent manner
    Suzuki, R
    Tobe, K
    Terauchi, Y
    Komeda, K
    Kubota, N
    Eto, K
    Yamauchi, T
    Azuma, K
    Kaneto, H
    Taguchi, T
    Koga, T
    German, MS
    Watada, H
    Kawamori, R
    Wright, CVE
    Kajimoto, Y
    Kimura, S
    Nagai, R
    Kadowaki, T
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (44) : 43691 - 43698
12345