Intra-amniotic delivery of CFTR expressing adenovirus does not reverse Cystic Fibrosis phenotype in inbred CFTR-knockout mice

被引：0

作者：

Buckley, S. M. K. ^{[1
,2
]}

Waddington, S. N. ^{[1
,2
]}

Jezzard, S. ^{[3
]}

Bergau, A. ^{[3
]}

Themis, M. ^{[4
]}

MacVinish, L. J. ^{[5
]}

Cuthbert, A. W. ^{[5
]}

Colledge, W. H. ^{[6
]}

Coutelle, C. ^{[3
]}

机构：

[1] UCL Royal Free & Univ Coll Med Sch, Dept Haematol, Haemophilia Ctr, London, England

[2] UCL Royal Free & Univ Coll Med Sch, Haemostasis Ctr, London, England

[3] Univ London Imperial Coll Sci Technol & Med, Dept Mol Med, Gene Therapy Res Grp, London, England

[4] Brunel Univ, Div Biosci, Genotoxic Grp, Uxbridge UB8 3PH, Middx, England

[5] Univ Cambridge, Addenbrookes Hosp, Dept Med, Cambridge CB2 2QQ, England

[6] Univ Cambridge, Dept Physiol Dev & Neurosci, Cambridge, England

来源：

HUMAN GENE THERAPY | 2008年 / 19卷 / 04期

关键词：

D O I：

暂无

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

P60

引用

页码：414 / 414

页数：1

共 26 条

[11] Foetal gene delivery in mice by intra-amniotic administration of retroviral producer cells and adenovirus
Douar, AM
Adebakin, S
Themis, M
Pavirani, A
Cook, T
Coutelle, C
GENE THERAPY, 1997, 4 (09) : 883 - 890
[12] TRANSFER OF THE CFTR CDNA TO CYSTIC-FIBROSIS PATIENTS AIRWAYS BY AEROSOL-MEDIATED DELIVERY OF A RECOMBINANT ADENOVIRUS
PAVIRANI, A
BELLON, G
JOURNAL OF CELLULAR BIOCHEMISTRY, 1995, : 370 - 370
[13] The "Goldilocks Effect" in Cystic Fibrosis:: identification of a lung phenotype in the cftr knockout and heterozygous mouse -: art. no. 21
Cohen, JC
Lundblad, LK
Bates, JHT
Levitzky, M
Larson, JE
BMC GENETICS, 2004, 5 (1)
[14] Roscovitine rescues alveolar macrophages function in mice expressing mutant cystic fibrosis transmembrane conductance regulator (CFTR)
Deriy, L. V.
Gomez, E. A.
Gallan, A. J.
Bindokas, V. P.
Meijer, L.
Nelson, D. J.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, 2010, 40 : 35 - 35
[15] Cystic fibrosis transmembrane conductance regulator with a shortened R domain rescues the intestinal phenotype of CFTR-/- mice
Ostedgaard, Lynda S.
Meyerholz, David K.
Vermeer, Daniel W.
Karp, Philip H.
Schneider, Lindsey
Sigmund, Curt D.
Welsh, Michael J.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, 108 (07) : 2921 - 2926
[16] rAAV-mediated gene transfer of a truncated CFTR rescues the cystic fibrosis phenotype in human intestinal organoids and CF mice
Vidovic, D.
Carlon, M. S.
da Cunha, M. F.
Dekkers, J. D.
Hollenhorst, M. I.
Bijvelds, M.
Ramalho, A. S.
Van den Haute, C.
Baekelandt, V.
De Boeck, K.
Sermet-Gaudelus, I.
de Jonge, H.
Beekman, J.
Edelman, A.
Gijsbers, R.
Debyser, Z.
HUMAN GENE THERAPY, 2015, 26 (10) : A104 - A104
[17] Cyclic Postnatal Ozone Exposure Alters Airway Epithelial Development in Wild-type and Cystic Fibrosis Transmembrane Receptor (CFTR) Knockout Mice
Fanucchi, M. V.
Ballinger, C. A.
Dickinson, D. A.
Postlethwait, M.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2010, 181
[18] EARLY LIFE EXPOSURE TO OZONE ALTERS AIRWAY EPITHELIAL RESPONSES IN WILD-TYPE & CYSTIC FIBROSIS TRANSMEMBRANE RECEPTOR (CFTR) KNOCKOUT MICE
Tuggle, K. L.
Asmellash, S.
Dickinson, D. A.
Mobley, J. A.
Fanucchi, M., V
PEDIATRIC PULMONOLOGY, 2010, : 265 - 265
[19] Colitis-induced bile duct injury in cystic fibrosis knockout mice: Further evidence of an association between cystic fibrosis transmembrane conductance regulator (CFTR) mutations and primary sclerosing cholangitis
Yantiss, RK
Zaman, MM
Blanco, PG
Nasser, IA
Sheth, SG
Shea, JC
Freedman, SD
LABORATORY INVESTIGATION, 2002, 82 (01) : 297A - 297A
[20] Colitis-induced bile duct injury in cystic fibrosis knockout mice: Further evidence of an association between cystic fibrosis transmembrane conductance regulator (CFTR) mutations and primary sclerosing cholangitis
Yantiss, RK
Zaman, MM
Blanco, PG
Nasser, IA
Sheth, SG
Shea, JC
Freedman, SD
MODERN PATHOLOGY, 2002, 15 (01) : 297A - 297A

← 1 2 3 →