Intra-amniotic delivery of CFTR expressing adenovirus does not reverse Cystic Fibrosis phenotype in inbred CFTR-knockout mice

被引：0

作者：

Buckley, S. M. K. ^{[1
,2
]}

Waddington, S. N. ^{[1
,2
]}

Jezzard, S. ^{[3
]}

Bergau, A. ^{[3
]}

Themis, M. ^{[4
]}

MacVinish, L. J. ^{[5
]}

Cuthbert, A. W. ^{[5
]}

Colledge, W. H. ^{[6
]}

Coutelle, C. ^{[3
]}

机构：

[1] UCL Royal Free & Univ Coll Med Sch, Dept Haematol, Haemophilia Ctr, London, England

[2] UCL Royal Free & Univ Coll Med Sch, Haemostasis Ctr, London, England

[3] Univ London Imperial Coll Sci Technol & Med, Dept Mol Med, Gene Therapy Res Grp, London, England

[4] Brunel Univ, Div Biosci, Genotoxic Grp, Uxbridge UB8 3PH, Middx, England

[5] Univ Cambridge, Addenbrookes Hosp, Dept Med, Cambridge CB2 2QQ, England

[6] Univ Cambridge, Dept Physiol Dev & Neurosci, Cambridge, England

来源：

HUMAN GENE THERAPY | 2008年 / 19卷 / 04期

关键词：

D O I：

暂无

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

P60

引用

页码：414 / 414

页数：1

共 26 条

[1] Intra-amniotic delivery of CFTR-expressing adenovirus does not reverse cystic fibrosis phenotype in inbred CFTR-knockout mice
Buckley, Suzanne M. K.
Waddington, S. N.
Jezzard, S.
Bergau, A.
Themis, M.
MacVinish, L. J.
Cuthbert, A. W.
Colledge, W. H.
Coutelle, C.
MOLECULAR THERAPY, 2008, 16 (05) : 819 - 824
[2] Intra-amniotic application of CFTR-expressing adenovirus does not reverse cystic fibrosis phenotype in inbred Cftr-knockout mice
Buckley, SMK
Waddington, SN
Jezzard, S
Themis, M
Colledge, WH
Coutelle, C
MOLECULAR THERAPY, 2003, 7 (05) : S200 - S200
[3] Disease phenotype of a ferret CFTR-knockout model of cystic fibrosis
Sun, Xingshen
Sui, Hongshu
Fisher, John T.
Yan, Ziying
Liu, Xiaoming
Cho, Hyung-Ju
Joo, Nam Soo
Zhang, Yulong
Zhou, Weihong
Yi, Yaling
Kinyon, Joann M.
Lei-Butters, Diana C.
Griffin, Michelle A.
Naumann, Paul
Luo, Meihui
Ascher, Jill
Wang, Kai
Frana, Timothy
Wine, Jeffrey J.
Meyerholz, David K.
Engelhardt, John F.
JOURNAL OF CLINICAL INVESTIGATION, 2010, 120 (09): : 3149 - 3160
[4] GENERATION OF A CFTR-KNOCKOUT RAT MODEL FOR CYSTIC FIBROSIS
Tuggle, K. L.
Gamber, K.
Cui, X.
Ji, D.
Chambers, A.
Bedwell, D. M.
Rowe, S. M.
Sorscher, E. J.
Fanucchi, M., V
PEDIATRIC PULMONOLOGY, 2012, 47 : 279 - 279
[5] Adenovirus-mediated in utero expression of CFTR does not improve survival of CFTR knockout mice
Davies, Lee A.
Varathalingam, Anusha
Painter, Hazel
Lawton, Anna E.
Sumner-Jones, Stephanie G.
Nunez-Alonso, Graciela A.
Chan, Mario
Munkonge, Felix
Alton, Eric W. F. W.
Hyde, Stephen C.
Gill, Deborah R.
MOLECULAR THERAPY, 2008, 16 (05) : 812 - 818
[6] Ventilatory Responses to Hypercapnia and Hypoxia in Conscious Cystic Fibrosis Knockout Mice Cftr−/−
Monique Bonora
Jean-Francois Bernaudin
Claude Guernier
Marie Christiane Brahimi-Horn
Pediatric Research, 2004, 55 : 738 - 746
[7] The "Goldilocks Effect" in Cystic Fibrosis: identification of a lung phenotype in the cftr knockout and heterozygous mouse
J Craig Cohen
Lennart KA Lundblad
Jason HT Bates
Michael Levitzky
Janet E Larson
BMC Genetics, 5
[8] Ventilatory responses to hypercapnia and hypoxia in conscious cystic fibrosis knockout mice Cftr-/-
Bonora, M
Bernaudin, JF
Guernier, C
Brahimi-Horn, MC
PEDIATRIC RESEARCH, 2004, 55 (05) : 738 - 746
[9] Aerosol administration of a recombinant adenovirus expressing CFTR to cystic fibrosis patients: A phase I clinical trial
Bellon, G
MichelCalemard, L
Thouvenot, D
Jagneaux, V
Poitevin, F
Malcus, C
Accart, N
Layani, MP
Aymard, M
Bernon, H
Bienvenu, J
Courtney, M
Doring, G
Gilly, B
Gilly, R
Lamy, D
Levrey, H
Morel, Y
Paulin, C
Perraud, F
Rodillon, L
Sene, C
So, S
TouraineMoulin, F
Schatz, C
Pavirani, A
HUMAN GENE THERAPY, 1997, 8 (01) : 15 - 25
[10] Foetal gene delivery in mice by intra-amniotic administration of retroviral producer cells and adenovirus
A-M Douar
S Adebakin
M Themis
A Pavirani
T Cook
C Coutelle
Gene Therapy, 1997, 4 : 883 - 890

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