Polypeptide backbone, Cβ and methyl group resonance assignments of the 24 kDa plectin repeat domain 6 from human protein plectin

被引:0
|
作者
Pulavarti, Surya V. S. R. K. [1 ,2 ]
Eletsky, Alexander [1 ,2 ]
Huang, Yuanpeng J. [3 ,4 ,5 ]
Acton, Thomas B. [3 ,4 ,5 ]
Xiao, Rong [3 ,4 ,5 ]
Everett, John K. [3 ,4 ,5 ]
Montelione, Gaetano T. [3 ,4 ,5 ,6 ]
Szyperski, Thomas [1 ,2 ]
机构
[1] SUNY Buffalo, Dept Chem, Buffalo, NY 14260 USA
[2] Northeast Struct Genom Consortium, Buffalo, NY 14260 USA
[3] Rutgers State Univ, Ctr Adv Biotechnol & Med, Piscataway, NJ 08854 USA
[4] Rutgers State Univ, Dept Mol Biol & Biochem, Piscataway, NJ 08854 USA
[5] Northeast Struct Genom Consortium, Piscataway, NJ 08854 USA
[6] Rutgers State Univ, Robert Wood Johnson Med Sch, Dept Biochem & Mol Biol, Piscataway, NJ 08854 USA
基金
美国国家卫生研究院;
关键词
Cytoskeletal linker protein; HCPIN; Plakin repeat domain; Plectin repeat domain; Selective isotope labeling; Structural genomics; CANCER;
D O I
10.1007/s12104-014-9559-x
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
The 500 kDa protein plectin is essential for the cytoskeletal organization of most mammalian cells and it is up-regulated in some types of cancer. Here, we report nearly complete sequence-specific polypeptide backbone, C-13(beta) and methyl group resonance assignments for 24 kDa human plectin(4403-4606) containing the C-terminal plectin repeat domain 6.
引用
收藏
页码:135 / 138
页数:4
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