Polypeptide backbone, Cβ and methyl group resonance assignments of the 24 kDa plectin repeat domain 6 from human protein plectin

被引：0

作者：

Pulavarti, Surya V. S. R. K. ^{[1
,2
]}

Eletsky, Alexander ^{[1
,2
]}

Huang, Yuanpeng J. ^{[3
,4
,5
]}

Acton, Thomas B. ^{[3
,4
,5
]}

Xiao, Rong ^{[3
,4
,5
]}

Everett, John K. ^{[3
,4
,5
]}

Montelione, Gaetano T. ^{[3
,4
,5
,6
]}

Szyperski, Thomas ^{[1
,2
]}

机构：

[1] SUNY Buffalo, Dept Chem, Buffalo, NY 14260 USA

[2] Northeast Struct Genom Consortium, Buffalo, NY 14260 USA

[3] Rutgers State Univ, Ctr Adv Biotechnol & Med, Piscataway, NJ 08854 USA

[4] Rutgers State Univ, Dept Mol Biol & Biochem, Piscataway, NJ 08854 USA

[5] Northeast Struct Genom Consortium, Piscataway, NJ 08854 USA

[6] Rutgers State Univ, Robert Wood Johnson Med Sch, Dept Biochem & Mol Biol, Piscataway, NJ 08854 USA

来源：

BIOMOLECULAR NMR ASSIGNMENTS | 2015年 / 9卷 / 01期

基金：

美国国家卫生研究院;

关键词：

Cytoskeletal linker protein; HCPIN; Plakin repeat domain; Plectin repeat domain; Selective isotope labeling; Structural genomics; CANCER;

D O I：

10.1007/s12104-014-9559-x

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

The 500 kDa protein plectin is essential for the cytoskeletal organization of most mammalian cells and it is up-regulated in some types of cancer. Here, we report nearly complete sequence-specific polypeptide backbone, C-13(beta) and methyl group resonance assignments for 24 kDa human plectin(4403-4606) containing the C-terminal plectin repeat domain 6.

引用

页码：135 / 138

页数：4

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