Polymorphisms in the P450C17 (17-hydroxylase/17,20-lyase)and P450C19 (aromatase) genes: Assosiation with serum sex steroids concentrations and bone mineral density in postmenopausal women

被引：0
|
作者：
Somner, J
Mclellan, S
Cheung, J
Mak, YT
Frost, ML
Knapp, KM
Wierebicki, AS
Wheeler, M
Fogelman, I
Ralston, SH
Hampson, G
机构：
[1] St Thomas Hosp, Dept Chem Pathol, London, England
[2] Guys Hosp, Osteoporosis Screening Unit, London SE1 9RT, England
[3] Univ Aberdeen, Sch Med, Dept Med & Therapeut, Bone Res Grp, Aberdeen AB9 1FX, Scotland
来源：
JOURNAL OF BONE AND MINERAL RESEARCH | 2003年 / 18卷 / 07期
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：1363 / 1363
页数：1
相关论文
共 50 条
  • [41] INHIBITION OF TESTICULAR MICROSOMAL CYTOCHROME-P-450 "(17ALPHA-HYDROXYLASE-C-17,20-LYASE) BY ESTROGENS
    ONODA, M
    HALL, PF
    ENDOCRINOLOGY, 1981, 109 (03) : 763 - 767
  • [42] Developmental gonadal expression of the transcription factor SET and its target gene, P450c17 (17α-hydroxylase/c17,20 lyase)
    Zhang, PL
    Compagnone, NA
    Fiore, C
    Vigne, JL
    Culp, P
    Musci, TJ
    Mellon, SH
    DNA AND CELL BIOLOGY, 2001, 20 (10) : 613 - 624
  • [43] A new compound heterozygous mutation (W17X, 436+5G→T) in the cytochrome P450c17 gene causes 17α-hydroxylase/17,20-lyase deficiency
    Suzuki, Y
    Nagashima, T
    Nomura, Y
    Onigata, K
    Nagashima, K
    Morikawa, A
    JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1998, 83 (01): : 199 - 202
  • [44] Development of a simple and rapid assay for the evaluation of inhibitors of human 17α-hydroxylase-C17,21-lyase (P450c17) by coexpression of P450c17 with NADPH-cytochrome-P450-reductase in Escherichia coli
    Ehmer, PB
    Jose, J
    Hartmann, RW
    JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 2000, 75 (01): : 57 - 63
  • [45] Regulation of 17,20 lyase activity by cytochrome b5 and by serine phosphorylation of P450c17
    Pandey, AV
    Miller, WL
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2005, 280 (14) : 13265 - 13271
  • [46] Cloning of zebrafish ovarian P450c17 (CYP 17, 17α-hydroxylase/17, 20-lyase) and characterization of its expression in gonadal and extra-gonadal tissues
    Wang, YJ
    Ge, W
    GENERAL AND COMPARATIVE ENDOCRINOLOGY, 2004, 135 (02) : 241 - 249
  • [47] Cytochrome P450c17-expressing Escherichia coli as a first-step screening system for 17α-hydroxylase-C17,20-lyase inhibitors
    Grigoryev, DN
    Kato, K
    Njar, VCO
    Long, BJ
    Ling, YZ
    Wang, X
    Mohler, J
    Brodie, AMH
    ANALYTICAL BIOCHEMISTRY, 1999, 267 (02) : 319 - 330
  • [48] A single amino acid substitution in the putative redox partner-binding site of P450c17 as cause of isolated 17,20-lyase deficiency
    BiasonLauber, A
    Leiberman, E
    Zachmann, M
    JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1997, 82 (11): : 3807 - 3812
  • [49] Developmental changes of serum steroids produced by cytochrome P450c17 in rat
    Tagawa, N
    Katagiri, M
    Kobayashi, Y
    STEROIDS, 2006, 71 (02) : 165 - 170
  • [50] Inhibitors of cytochrome P450(17 alpha) (17 alpha-hydroxylase/C17,20 lyase)
    Barrie, SE
    Jarman, M
    ENDOCRINE-RELATED CANCER, 1996, 3 (01) : 25 - 39
12345