The possible role of glutathione-S-transferase activity in diabetic nephropathy

被引：22

作者：

Tesauro, M. ^{[1
]}

Nistico, S. ^{[2
]}

Noce, A. ^{[1
]}

Tarantino, A. ^{[1
]}

Marrone, G. ^{[1
]}

Costa, A. ^{[3
]}

Rovella, V. ^{[1
]}

Di Cola, G. ^{[1
]}

Campia, U. ^{[4
]}

Lauro, D. ^{[5
]}

Cardillo, C. ^{[6
]}

Di Daniele, N. ^{[1
]}

机构：

[1] Univ Roma Tor Vergata, Div Nephrol & Hypertens, Dept Syst Med, Rome, Italy

[2] Univ Catanzaro Magna Graecia, Dept Hlth Sci, Catanzaro, Italy

[3] Campus Biomed Univ Rome, Ctr Integrated Res, Rome, Italy

[4] MedStar Cardiovasc Res Network Washington, Washington, DC USA

[5] Univ Roma Tor Vergata, Endocrinol Unit, Rome, Italy

[6] Catholic Univ, Internal Med, Rome, Italy

来源：

INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY | 2015年 / 28卷 / 01期

关键词：

biomarkers; diabetic nephropathy; glutathione-S-transferase; oxidative stress; TYPE-2; MICROALBUMINURIA; POLYMORPHISMS; EVOLUTION; MELLITUS; VALUES; GSTM1; T1;

D O I：

10.1177/0394632015572564

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The most common cause of end stage renal disease is diabetic nephropathy. An early diagnosis may allow an intervention to slow down disease progression. Recently, it has been hypothesized that glutathione-S-transferase (GST) activity may be a marker of severity of chronic kidney disease. In particular, a lower GST activity is present in healthy subjects compared to patients with nephropathy. In the present review we illustrate the scientific evidence underlying the possible role of GST activity in the development of diabetic nephropathy and we analyze its usefulness as a possible early biomarker of this diabetic complication.

引用

页码：129 / 133

页数：5

共 50 条

[41] ISOLATION OF GLUTATHIONE-S-TRANSFERASE INHIBITORS
KOMAGATA, D
SAWA, R
KINOSHITA, N
IMADA, C
SAWA, T
NAGANAWA, H
HAMADA, M
OKAMI, Y
TAKEUCHI, T
JOURNAL OF ANTIBIOTICS, 1992, 45 (10): : 1681 - 1683
[42] GLUTATHIONE-S-TRANSFERASE IN HUMAN BILE
HOWIE, AF
HAYES, PC
BOUCHIER, IAD
HAYES, JD
BECKETT, GJ
CLINICA CHIMICA ACTA, 1989, 184 (03) : 269 - 278
[43] GLUTATHIONE-S-TRANSFERASE IN HUMAN ORGANS
SHERMAN, M
TITMUSS, S
KIRSCH, RE
BIOCHEMISTRY INTERNATIONAL, 1983, 6 (01): : 109 - 118
[44] GLUTATHIONE-S-TRANSFERASE OF ANIMAL SPECIES
SATOH, K
SATOH, K
NIPPON NOGEIKAGAKU KAISHI-JOURNAL OF THE JAPAN SOCIETY FOR BIOSCIENCE BIOTECHNOLOGY AND AGROCHEMISTRY, 1992, 66 (10): : 1487 - 1490
[45] CYCLOSPORIN AND URINE GLUTATHIONE-S-TRANSFERASE
FEINFELD, D
BENVENISTY, A
DAGATI, V
HARDY, M
KIDNEY INTERNATIONAL, 1985, 28 (02) : 394 - 394
[46] Development of probes for glutathione-S-transferase
Fujikawa, Haruka
Shishido, Yuko
Murakami, Yuko
Sekido, Yoshitaka
Abe, Hiroshi
CANCER SCIENCE, 2018, 109 : 731 - 731
[47] GLUTATHIONE-S-TRANSFERASE IN HUMAN BRAIN
CARDER, PJ
HUME, R
FRYER, AA
STRANGE, RC
LAUDER, J
BELL, JE
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, 1990, 16 (04) : 293 - 303
[48] Possible role for glutathione-S-transferase in the oligozoospermia elicited by acute zearalenone administration in Swiss albino mice
Boeira, Silvana Peterini
Borges Filho, Carlos
Del'Fabbro, Lucian
Freire Royes, Luiz Fernando
Jesse, Cristiano Ricardo
Oliveira, Mauro Schneider
Furian, Ana Flavia
TOXICON, 2012, 60 (03) : 358 - 366
[49] POSSIBLE ROLE OF PLACENTAL GLUTATHIONE-S-TRANSFERASE (GST-P) DURING CHEMICAL HEPATOCARCINOGENESIS IN THE RAT
OULDELHKIM, M
MARTIN, M
DECLOITRE, F
MUTATION RESEARCH, 1990, 234 (06): : 395 - 396
[50] Role of glutathione-S-transferase in determining the activity of brostallicin in human prostate cancer cells.
Farrell, N
Montero, EI
Hegmans, A
Qu, Y
CLINICAL CANCER RESEARCH, 2003, 9 (16) : 6082S - 6082S

← 1 2 3 4 5 →