Racemization processes at a quaternary carbon center in the context of the asymmetric Michael reaction

被引：17

作者：

Tan, K

Alvarez, R

Nour, M

Cavé, C

Chiaroni, A

Riche, C

d'Angelo, J

机构：

[1] Ctr Etud Pharmaceut, F-92296 Chatenay Malabry, France

[2] ICSN, CNRS, F-91198 Gif Sur Yvette, France

[3] UFR Pharm, Unite Mol Interet Biol, F-21079 Dijon, France

[4] Univ Vigo, Dept Quim Organ, Vigo 36200, Spain

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 30期

关键词：

asymmetric synthesis; Michael reaction; quaternary carbon center; racemization; X-ray crystallography;

D O I：

10.1016/S0040-4039(01)00926-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Several examples of racemization process at a quaternary carbon center affecting Michael adducts were reported. A brief statement to prevent the occurrence of the interfering retro-Michael reaction was also presented. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：5021 / 5023

页数：3

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